Correction: Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis [0.03%]
脂肪酸羟化酶调控鞘氨醇代谢失常会暴露癌症转移的代谢脆弱性以进行靶向治疗(校正)
Xuantong Zhou,Furong Huang,Gang Ma et al.
Xuantong Zhou et al.
Dopamine as a teaching signal: understanding its role in shaping individual behavior [0.03%]
多巴胺作为教学信号:理解其在塑造个体行为中的作用
Seung Chan Kim,Sehwan Kim,Sang Ryong Kim
Seung Chan Kim
Targeting TRPV6/CXCR4 complexes prevents castration-resistant prostate cancer metastasis to the bone [0.03%]
靶向TRPV6 / CXCR4复合物可防止去势抵抗性前列腺癌骨转移
Clément Cordier,Aurélien Haustrate,Adriana Mihalache et al.
Clément Cordier et al.
Bone metastasis most commonly occurs in castration-resistant prostate cancer (CRPC). The TRPV6 calcium channel is absent in healthy prostate tissue, but its expression increases considerably during cancer progression. We hypothesized that c...
UGCG and the glycosphingolipid rheostat: a metabolic checkpoint governing immune activation and tumor immune evasion [0.03%]
UGCG和糖脂雷斯塔特:调控免疫激活和肿瘤免疫逃逸的代谢检查点
Sumei Chen,Xiang Wang,Youssef Jounaidi
Sumei Chen
Understanding the toxicity induced by radiation-triggered neuroinflammation and the on-demand design of targeted peptide nanodrugs [0.03%]
辐射诱发的神经炎症毒性的认识以及按需设计靶向肽纳米药物
Yue Shang,Xueyin Hu,Meixia Ren et al.
Yue Shang et al.
Radiation-induced brain injury (RIBI) represents a severe complication of cranial radiotherapy, substantially diminishing patients' quality of life. Unlike conventional brain injuries, RIBI evokes a unique chronic neuroinflammatory response...
Correction: Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness [0.03%]
订正:癌细胞采用微环境神经信号活化核线粒体协调以获得干细胞特性
Bin He,Rui Gao,Shasha Lv et al.
Bin He et al.
Pancancer outcome prediction via a unified weakly supervised deep learning model [0.03%]
基于统一的弱监督深度学习模型的泛癌预后预测
Wei Yuan,Yijiang Chen,Biyue Zhu et al.
Wei Yuan et al.
Accurate prognosis prediction is essential for guiding cancer treatment and improving patient outcomes. While recent studies have demonstrated the potential of histopathological images in survival analysis, existing models are typically dev...
"Good" fats, bad news: HDL-delivered vitamin E shields tumors from ferroptosis [0.03%]
“好”脂肪与坏消息:HDL递送的维生素E使肿瘤免受铁死亡攻击
Dong Wook Choi,Eun-Woo Lee
Dong Wook Choi
Correction: Aberrant Notch-signaling promotes tumor angiogenesis in esophageal squamous-cell carcinoma [0.03%]
纠正: notch信号转导异常可促进食管鳞癌肿瘤血管生成
Cainan Li,Pujie Wu,Xiaoting Xie et al.
Cainan Li et al.
Bicarbonate-integrated transarterial chemoembolization (TACE) in real-world hepatocellular carcinoma [0.03%]
碳酸氢钠整合的经动脉化疗栓塞(TACE)治疗肝细胞癌的真实世界研究
Kai Jin,Siying Zeng,Bin Li et al.
Kai Jin et al.
The objective response rate of conventional transarterial chemoembolization (TACE) for locoregional control of hepatocellular carcinoma (HCC) is approximately 50%. We previously developed bicarbonate-integrated TACE, termed TILA-TACE, which...