Starving tumor, feeding metastasis: a warning about low-carbohydrate diets in cancer therapy [0.03%]
Byeongsoo Kim,BuHyun Youn
Byeongsoo Kim
Circulating miR-18b-3p is a novel biomarker predicting chemo-radiotherapy induced oral mucositis in head and neck cancer [0.03%]
Claudio Pulito,Renata Brandi,Rosanna Sestito et al.
Claudio Pulito et al.
Dynamic transcriptional immune landscape in response to NK-cell therapy combined with gemcitabine plus S-1 in advanced pancreatic cancer: a phase 1b/2 trial [0.03%]
Qin Tan,Yifei Li,Caixia Liu et al.
Qin Tan et al.
Despite advancements in several malignancies, the treatment atlas of natural killer (NK) cell therapy for pancreatic cancer remains inadequate, and the dynamic immune landscape underlying the various responses is still incompletely understo...
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury [0.03%]
Khalil Mallah,Carsten Krieg,Devin Hatchell et al.
Khalil Mallah et al.
Repeated mild closed head injury (rmCHI) is a significant public health concern, and this type of repetitive injury is garnering increasing attention, not least because of its increasing incidence in sports. The underlying neuroimmune mecha...
Multidimensional tumor-blood profiling uncovers systemic lymphocyte-monocyte imbalance in pituitary neuroendocrine tumors [0.03%]
多维度肿瘤-血液检测发现垂体神经内分泌瘤存在系统性淋巴细胞-单核细胞失衡现象
Yuting Dai,Shaojian Lin,Junchen Wu et al.
Yuting Dai et al.
Pituitary neuroendocrine tumors (PitNETs) are pathologically characterized by dysregulation of neuroendocrine function and systemic disruption of hormonal homeostasis, yet their regulatory effects on peripheral immune networks remain poorly...
Pyruvate kinase M2 -mediated histone lactylation alters three-dimensional genomic architecture in polycystic ovary syndrome [0.03%]
丙酮酸激酶M2介导的组蛋白乳酸化可改变多囊卵巢综合征中的三维基因组结构
Chuanjin Yu,Tingting Liu,Yishu Wang et al.
Chuanjin Yu et al.
Polycystic ovary syndrome (PCOS) is a frequent endocrine and metabolic imbalance that typically occurs in women of reproductive age. Its molecular pathophysiology is yet unknown, especially the ovarian cellular metabolic inefficiency that c...
Therapeutic targeting of endothelial calcium signaling accelerates the resolution of lung injury [0.03%]
针对内皮细胞钙信号通路的治疗可加速肺损伤的恢复
Wan Ching Chan,Man Long Kwok,Xinyan Qu et al.
Wan Ching Chan et al.
Acute respiratory distress syndrome (ARDS) is a severe pulmonary disease characterized by acute, noncardiogenic pulmonary edema and hypoxemia leading to respiratory failure. It is induced by a diverse array of etiologies, including recent S...
Family with sequence similarity 114 member A1 orchestrates immune evasion in triple-negative breast cancer [0.03%]
含有与家族114成员A1相似序列的蛋白在三阴性乳腺癌中参与免疫逃逸调控
Wenhao Zhang,Yanzhi Gai,Mengxue Qiao et al.
Wenhao Zhang et al.
Immune checkpoint blockade (ICB) therapy, which has revolutionized cancer treatment, has been approved for the treatment of triple-negative breast cancer (TNBC). Unfortunately, most patients with TNBC are either not eligible for treatment o...
Engineered butyrate-producing yeasts mitigate Alzheimer-associated phenotypes [0.03%]
工程化丁酸盐产生酵母菌可缓解与阿尔茨海默病相关的表型
Biao Zhang,Zhiyu Sun,Weihong Song et al.
Biao Zhang et al.
Benjamin H Mullish,Lauren A Roberts,Horace R T Williams
Benjamin H Mullish