Publisher Correction: Interplay between cohesin and RNA polymerase II in regulating chromatin interactions and gene transcription [0.03%]
出版更正：凝聚素和RNA聚合酶II在调节染色质相互作用和基因转录方面的相互作用
Minji Kim,Ping Wang,Patricia A Clow et al.
Minji Kim et al.
Published Erratum
Nature structural & molecular biology. 2026 Jul 3. DOI:10.1038/s41594-026-01850-3 2026
James M Jusuf,Jin H Yang,Jack Toppen et al.
James M Jusuf et al.
Three-dimensional genomics methods such as Hi-C and Micro-C have uncovered chromatin loops across the genome and linked these loops to gene regulation. However, these methods only measure three-dimensional interaction probabilities on a rel...
Adrian Henggeler,Fena Ochs
Adrian Henggeler
Transcriptional readthrough progresses from incidental byproduct to therapeutic opportunity [0.03%]
转录读穿现象从意外产物转变为潜在的治疗机会
Agata Stępień,Martyna Plens-Gałąska,Kinga Kamieniarz-Gdula
Agata Stępień
Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity [0.03%]
ATRX通过与9-1-1和CST复合物的多种功能相互作用来维护复制叉和端粒的完整性的独特机制
Sandra Segura-Bayona,Marija Maric,Tohru Takaki et al.
Sandra Segura-Bayona et al.
Mutations in the ATRX chromatin remodeler confer a predisposition to a developmental genetic disorder and cancer, but how ATRX safeguards genome and telomere stability remains unresolved. Here, we uncover critical dependencies for the CTC1-...
Structurally defining neurokinin selectivity to improve NK2R agonists [0.03%]
通过结构定义神经激肽的选择性以改进NK2受体激动剂
Artem Pavlovskyi,Yinhang Ren,María Gestal-Mato et al.
Artem Pavlovskyi et al.
Incretin-based obesity pharmacotherapies have revolutionized patient care but act predominantly by reducing food intake. Approaches that increase energy expenditure could improve efficacy but remain challenging to harness. Recently, neuroki...
Ishan Deshpande,Nobuhiko Kayagaki
Ishan Deshpande
Structural basis of asymmetric transcription through a composite nucleosome formed by a hexasome and an octasome [0.03%]
六聚核小体和八聚核小体形成的复合核小体的不对称转录的结构基础
Zhihui Chen,Cheng-Han Ho,Hiroki Tanaka et al.
Zhihui Chen et al.
The overlapping dinucleosome (OLDN), a composite chromatin particle consisting of a hexasome and a canonical octasome, forms immediately downstream of transcription start sites, probably through chromatin remodeling activity, and has been p...