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A competitive regulatory mechanism of the Chd1 remodeler is integral to distorting nucleosomal DNA

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The Chd1 chromatin remodeler repositions nucleosomes into evenly spaced arrays, a characteristic of most eukaryotic genes. Here we show that the yeast Chd1 remodeler requires two activating segments to distort nucleosomal DNA into an A-form-like conformation, ... ...