Trichophyton concentricum fungal infections and skin microbiomes of Indigenous Peninsular Malaysians [0.03%]
马来半岛原住民的头癣菌（Trichophyton concentricum）感染及皮肤微生物群
Yi Xian Er,Soo Ching Lee,Chioma Aneke et al.
Yi Xian Er et al.
Recent outbreaks of multidrug-resistant fungi infecting human skin emphasize the importance of understanding fungal pathophysiology and spread. In efforts to address health concerns with various Indigenous Peninsular Malaysians (Orang Asli ...
Rebecka J Sepela,Hao Jiang,Yern-Hyerk Shin et al.
Rebecka J Sepela et al.
Microbial communities coat nearly every surface in the environment and have co-existed with animals throughout evolution. Whether animals exploit omnipresent microbial cues to navigate their surroundings is not well understood. Octopuses us...
Joel Vizueta,Zijun Xiong,Guo Ding et al.
Joel Vizueta et al.
Ants originated over 150 million years ago through an irreversible transition to superorganismal colony life. Comparative analyses of 163 ant genomes, including newly generated whole-genome sequences of 145 ant species, reveal extensive gen...
Tamir Eliav,Shir R Maimon,Ayelet Sarel et al.
Tamir Eliav et al.
The hippocampus is crucial for memory. Memory consolidation is thought to be subserved by hippocampal "replays" of previously experienced trajectories. However, it is unknown how the brain replays long spatial trajectories in very large, na...
A percolation phase transition controls complement protein coating of surfaces [0.03%]
渗流相变控制补体蛋白的表面附着现象
Zhicheng Wang,Sahil Kulkarni,Jia Nong et al.
Zhicheng Wang et al.
When a material enters the body, it is immediately attacked by hundreds of proteins, organized into complex networks of binding interactions and reactions. How do such complex systems interact with a material, "deciding" whether to attack? ...
Senescence-resistant human mesenchymal progenitor cells counter aging in primates [0.03%]
一种抗衰老的人体间充质干细胞能对抗灵长类动物的衰老
Jinghui Lei,Zijuan Xin,Ning Liu et al.
Jinghui Lei et al.
Aging is characterized by a deterioration of stem cell function, but the feasibility of replenishing these cells to counteract aging remains poorly defined. Our study addresses this gap by developing senescence (seno)-resistant human mesenc...
Perturb-Multimodal: A platform for pooled genetic screens with imaging and sequencing in intact mammalian tissue [0.03%]
Perturb-多模态：在完整哺乳动物组织中进行成像和测序的汇集遗传筛选平台
Reuben A Saunders,William E Allen,Xingjie Pan et al.
Reuben A Saunders et al.
Metazoan life requires the coordinated activities of thousands of genes in spatially organized cell types. Understanding the basis of tissue function requires approaches to dissect the genetic control of diverse cellular and tissue phenotyp...
Unraveling Mendel's final mysteries: A genomic retelling of pea genetics [0.03%]
解开孟德尔最后的谜题：豌豆基因组学的故事
Murukarthick Jayakodi,Preethi Purushotham,Nils Stein
Murukarthick Jayakodi
Using modern genomic tools, Feng et al. revisited Mendel's seven pea traits in a recent Nature study, uncovering the molecular genetic basis of all of them, including the three unresolved ones: pod color, pod shape, and flower position. The...
Meghan B Ward,Giedre Krenciute
Meghan B Ward
Understanding acute and long-term adverse events following CAR T cell therapy for cancer remains a crucial area of investigation as CAR T cells become more prominent in the clinic. In this issue of Cell, Geraghty and Acosta-Alvarez et al. i...
Dopamine encodes deep network teaching signals for individual learning trajectories [0.03%]
多巴胺编码深度网络教学信号以进行个体学习路径研究
Samuel Liebana,Aeron Laffere,Chiara Toschi et al.
Samuel Liebana et al.
Striatal dopamine plays fundamental roles in fine-tuning learned decisions. However, when learning from naive to expert, individuals often exhibit diverse learning trajectories, defying understanding of its underlying dopaminergic mechanism...