Correction: Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness [0.03%]
订正：癌细胞采用微环境神经信号活化核线粒体协调以获得干细胞特性
Bin He,Rui Gao,Shasha Lv et al.
Bin He et al.
Pancancer outcome prediction via a unified weakly supervised deep learning model [0.03%]
基于统一的弱监督深度学习模型的泛癌预后预测
Wei Yuan,Yijiang Chen,Biyue Zhu et al.
Wei Yuan et al.
Accurate prognosis prediction is essential for guiding cancer treatment and improving patient outcomes. While recent studies have demonstrated the potential of histopathological images in survival analysis, existing models are typically dev...
"Good" fats, bad news: HDL-delivered vitamin E shields tumors from ferroptosis [0.03%]
“好”脂肪与坏消息：HDL递送的维生素E使肿瘤免受铁死亡攻击
Dong Wook Choi,Eun-Woo Lee
Dong Wook Choi
Correction: Aberrant Notch-signaling promotes tumor angiogenesis in esophageal squamous-cell carcinoma [0.03%]
纠正： notch信号转导异常可促进食管鳞癌肿瘤血管生成
Cainan Li,Pujie Wu,Xiaoting Xie et al.
Cainan Li et al.
Bicarbonate-integrated transarterial chemoembolization (TACE) in real-world hepatocellular carcinoma [0.03%]
碳酸氢钠整合的经动脉化疗栓塞(TACE)治疗肝细胞癌的真实世界研究
Kai Jin,Siying Zeng,Bin Li et al.
Kai Jin et al.
The objective response rate of conventional transarterial chemoembolization (TACE) for locoregional control of hepatocellular carcinoma (HCC) is approximately 50%. We previously developed bicarbonate-integrated TACE, termed TILA-TACE, which...
Focal adhesion kinase/Src family kinase axis-mediated tyrosine phosphorylation of metabolic enzymes facilitates tumor metastasis [0.03%]
黏附斑激酶/Src家族激酶轴介导的代谢酶酪氨酸磷酸化促进肿瘤转移
Jie Chen,Jing Zhang,Yuheng Zhu et al.
Jie Chen et al.
Lymph node metastasis is crucial for esophageal squamous cell carcinoma (ESCC) malignancy. However, the molecular drivers and related mechanisms of lymph node metastasis in ESCC cells are unclear. In the present study, we found that the tyr...
Arterial stiffness and vascular aging: mechanisms, prevention, and therapy [0.03%]
动脉僵硬度与血管衰老：机制、预防和治疗
Maximilian Jonathan Herzog,Patrick Müller,Katharina Lechner et al.
Maximilian Jonathan Herzog et al.
Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. The central underlying mechanisms of cardiovascular diseases are vascular aging and associated arterial stiffness. Arterial stiffness is characterized by st...
Neutrophil-specific targeting of STAT3 impairs tumor progression via the expansion of cytotoxic CD8+ T cells [0.03%]
STAT3特异性中性粒细胞靶向通过增加细胞毒性CD8+T细胞的增殖来抑制肿瘤进展
Irem Ozel,Guanyu Sha,Agnieszka Będzińska et al.
Irem Ozel et al.
Neutrophils have emerged as key players in tumor progression and are often associated with poor prognosis. Despite ongoing efforts to target neutrophil functions in cancer, therapeutic success has been limited. In this study, we addressed t...
Neuronal immunoproteasome and PFKFB3-forced glycolysis: key players in multiple sclerosis [0.03%]
神经免疫蛋白酶体和PFKFB3强制性糖酵解：多发性硬化的关键因素
Claudia Rodríguez-López,Juan P Bolaños,José J Lucas
Claudia Rodríguez-López
Single amino acid substitution in Hendra virus attachment glycoprotein induces cross-neutralizing antibodies against Nipah virus [0.03%]
亨德拉病毒糖蛋白单氨基酸替代诱导尼帕病毒交叉中和抗体产生
Yaohui Li,Xiaoyan Huang,Ruihua Li et al.
Yaohui Li et al.
Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic henipaviruses within the Paramyxoviridae family, causing severe respiratory and neurological diseases in humans and animals with fatality rates up to 75%, and no licensed human ...