m6A and the NEXT complex direct Xist RNA turnover and X-inactivation dynamics [0.03%]
m6A和NEXT复合体通过直接调控XistRNA的周转来影响X染色体失活的动态过程
Guifeng Wei,Heather Coker,Lisa Rodermund et al.
Guifeng Wei et al.
X-chromosome inactivation (XCI) in mammals is orchestrated by the noncoding RNA X-inactive-specific transcript (Xist) that, together with specific interacting proteins, functions in cis to silence an entire X chromosome. Defined sites on Xi...
Chatrin Chatrin,Kang Zhu,Ivan Ahel
Chatrin Chatrin
tRNA as an assembly chaperone for a macromolecular transcription-processing complex [0.03%]
tRNA作为组装辅助因子促进巨分子转录加工复合物的形成
Julia Bartuli,Stefan Jungwirth,Manisha Dixit et al.
Julia Bartuli et al.
Transfer RNAs (tRNAs) are widely recognized for their role in translation. Here, we describe a previously unidentified function of tRNA as an assembly chaperone. During poxviral infection, tRNAGln/Arg lacking the anticodon mcm5s2U34 modific...
Addendum: Retinoic acid signaling is critical during the totipotency window in early mammalian development [0.03%]
附录：视黄酸信号在哺乳动物早期发育全能性窗口期至关重要
Ane Iturbide,Mayra L Ruiz Tejada Segura,Camille Noll et al.
Ane Iturbide et al.
Yi-Lan Chen,Jin-Der Wen
Yi-Lan Chen
Interactions between the genome and the nuclear lamina are multivalent and cooperative [0.03%]
基因组与核纤层之间的相互作用是多价和协作的
Lise Dauban,Mathias Eder,Marcel de Haas et al.
Lise Dauban et al.
Lamina-associated domains (LADs) are megabase-sized genomic regions that interact with the nuclear lamina (NL). It is not yet understood how their interactions with the NL are encoded in their DNA. Here we designed an efficient LAD 'scrambl...
Author Correction: HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly [0.03%]
作者更正：HIV-1依赖其未成熟的晶格招募IP6以进行衣壳组装成熟
Nadine Renner,Alex Kleinpeter,Donna L Mallery et al.
Nadine Renner et al.
Published Erratum
Nature structural & molecular biology. 2025 Aug 29. DOI:10.1038/s41594-025-01667-6 2025
Dynamic TOM-TIM23 supercomplex directs mitochondrial protein translocation and sorting [0.03%]
动态的TOM-TIM23超级复合体指导线粒体蛋白转运和分类
Yuqi Yang,Shanshan Wang,Guopeng Wang et al.
Yuqi Yang et al.
The mitochondrial translocase of the outer membrane (TOM) and translocase of the inner membrane 23 (TIM23) complexes are coupled to control protein import across the outer and inner membranes, respectively. However, the mechanisms of protei...
Author Correction: Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1 [0.03%]
作者更正：RYBP-PRC1阅读和编写组蛋白泛素化的结构基础
Maria Ciapponi,Elena Karlukova,Sven Schkölziger et al.
Maria Ciapponi et al.
Published Erratum
Nature structural & molecular biology. 2025 Aug 27. DOI:10.1038/s41594-025-01674-7 2025