Yihu Xie,Yi Ren
Yihu Xie
Structural basis for the synergistic assembly of the snRNA export complex [0.03%]
snRNA输出复合物协同装配的结构基础
Etienne Dubiez,William Garland,Maja Finderup Brask et al.
Etienne Dubiez et al.
The nuclear cap-binding complex (CBC) and its partner Arsenite-Resistance Protein 2 (ARS2) regulate the fate of RNA polymerase II transcripts via mutually exclusive interactions with RNA effectors. One such effector is PHAX, which mediates ...
Sandra M G Dias
Sandra M G Dias
Yousuf A Khan,K Ian White,Richard A Pfuetzner et al.
Yousuf A Khan et al.
SNARE (soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein receptor) proteins drive membrane fusion at different cell compartments as their core domains zipper into a parallel four-helix bundle. After fusion, these bundles ar...
Bruce Stillman,John F X Diffley,Janet H Iwasa
Bruce Stillman
The initiation of DNA replication in eukaryotic cells begins with the assembly of pre-replicative complexes (pre-RCs) at many sites along each chromosome during the G1 phase of the cell cycle. Pre-RCs license each chromosome for duplication...
Structural basis and functional roles for Toll-like receptor binding to Latrophilin in C. elegans development [0.03%]
toll样受体结合_latrophilin在秀丽隐杆线虫发育中的结构基础和功能作用
Gabriel Carmona-Rosas,Jingxian Li,Jayson J Smith et al.
Gabriel Carmona-Rosas et al.
Latrophilins are conserved adhesion-type G-protein-coupled receptors associated with embryonic defects and lethality. However, their mechanistic roles and ligands in embryogenesis remain unknown. Here, we identified TOL-1, the sole Toll-lik...
Chew Theng Lim,Thomas C R Miller,Kang Wei Tan et al.
Chew Theng Lim et al.
Eukaryotic DNA replication initiates from genomic loci known as origins. At budding yeast origins like ARS1, a double hexamer (DH) of the MCM replicative helicase is assembled by origin recognition complex (ORC), Cdc6 and Cdt1 by sequential...
Yanhe Zhao,Kangkang Song,Amirrasoul Tavakoli et al.
Yanhe Zhao et al.
Cilia are microtubule-based organelles that have important roles in cell sensing, signaling and motility. Recent studies have revealed the atomic structures of many multicomponent ciliary complexes, elucidating their mechanisms of action. H...
Zhuang Xiao,Mingxi Liu
Zhuang Xiao