Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213
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Pathogens have evolved diverse strategies to counteract host immunity. Ubiquitylation of lipopolysaccharide (LPS) on cytosol-invading bacteria by the E3 ligase RNF213 creates 'eat me' signals for antibacterial autophagy, but whether and how cytosol-adapted b... ...