Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers [0.03%]
SPIN90二聚体介导的由Arp2/3活化双向成肌动蛋白组装
Tianyang Liu,Luyan Cao,Miroslav Mladenov et al.
Tianyang Liu et al.
Branched actin networks nucleated by the Arp2/3 complex have critical roles in various cellular processes, from cell migration to intracellular transport. However, when activated by WISH/DIP/SPIN90-family proteins, Arp2/3 nucleates linear a...
Cameron J Glasscock,Robert J Pecoraro,Ryan McHugh et al.
Cameron J Glasscock et al.
Sequence-specific DNA-binding proteins (DBPs) have critical roles in biology and biotechnology and there has been considerable interest in the engineering of DBPs with new or altered specificities for genome editing and other applications. ...
Dimitris Typas
Dimitris Typas
m6A and the NEXT complex direct Xist RNA turnover and X-inactivation dynamics [0.03%]
m6A和NEXT复合体通过直接调控XistRNA的周转来影响X染色体失活的动态过程
Guifeng Wei,Heather Coker,Lisa Rodermund et al.
Guifeng Wei et al.
X-chromosome inactivation (XCI) in mammals is orchestrated by the noncoding RNA X-inactive-specific transcript (Xist) that, together with specific interacting proteins, functions in cis to silence an entire X chromosome. Defined sites on Xi...
Chatrin Chatrin,Kang Zhu,Ivan Ahel
Chatrin Chatrin
tRNA as an assembly chaperone for a macromolecular transcription-processing complex [0.03%]
tRNA作为组装辅助因子促进巨分子转录加工复合物的形成
Julia Bartuli,Stefan Jungwirth,Manisha Dixit et al.
Julia Bartuli et al.
Transfer RNAs (tRNAs) are widely recognized for their role in translation. Here, we describe a previously unidentified function of tRNA as an assembly chaperone. During poxviral infection, tRNAGln/Arg lacking the anticodon mcm5s2U34 modific...
Addendum: Retinoic acid signaling is critical during the totipotency window in early mammalian development [0.03%]
附录:视黄酸信号在哺乳动物早期发育全能性窗口期至关重要
Ane Iturbide,Mayra L Ruiz Tejada Segura,Camille Noll et al.
Ane Iturbide et al.
Yi-Lan Chen,Jin-Der Wen
Yi-Lan Chen