Construction of a whole-brain panorama for glioma vasculature reveals tumor heterogeneity and blood-brain barrier disruption [0.03%]
胶质瘤血管全景图的构建揭示了肿瘤异质性和血脑屏障破坏
Chenxi Huang,Xiaohong Xin,Xiaoxu Hao et al.
Chenxi Huang et al.
Vasculature-induced tumor tissue heterogeneity impedes predicable drug distribution and presents notable challenges for optimizing nanoparticle (NP)-based drug delivery. However, mesoscopic-scale tumor heterogeneity across entire brain rema...
High-performance reversible adhesive from PET waste for underwater, structural, and pressure-sensitive applications [0.03%]
一种高性能的可逆粘合剂，由PET废料制备，适用于水下、结构性和压敏性应用
Mary K Danielson,Bobby G Sumpter,Zoriana Demchuk et al.
Mary K Danielson et al.
Developing versatile, tough, and sustainable adhesives that function effectively in both wet and dry environments is a major challenge. Here, we report a bioinspired design for versatile, tough, and reversible adhesives upcycled from consum...
A superstrong, decarbonizing structural material enabled by microbe-assisted cell wall engineering via a biomechanochemical process [0.03%]
一种由微生物辅助的细胞壁工程通过生物机械化学过程使超强度和减少碳排放的结构材料成为可能
Ziyang Lu,Luhe Qi,Junqing Chen et al.
Ziyang Lu et al.
Lightweight and high-strength structural materials promise exceptional applications in advanced engineering fields. As a productive and sustainable material, wood exhibits exceptional potential to be converted into high-performance structur...
Direct approach to high-resolution, square-lattice alternating nanodot array by breaking hexagonal symmetry of block copolymer spheres [0.03%]
打破_HEX_球形拓扑结构的二维周期性嵌段共聚物体系中的直接竞争方形阵列相
Seong Eun Kim,Gabriella P Irianti,Hyunwoo Kim et al.
Seong Eun Kim et al.
Expanding the morphological spectrum of block copolymer (BCP) self-assembly remains a notable challenge in BCP-based bottom-up nanofabrication. We present a simple method to fabricate unconventional yet crucial structures of sphere-forming ...
Multienergy x-ray detection and imaging enabled by working voltage regulating unipolar carrier collection in perovskite detectors [0.03%]
利用钙钛矿探测器的工作电压调节单极载流收集进行多能量X射线检测和成像
Yuwei Li,Xin Wang,Yijing Ding et al.
Yuwei Li et al.
Multienergy x-ray imaging can provide additional substance information beyond morphology in conventional energy-integration imaging. The predominant approach, single photon counting, sets stringent requirements on low x-ray flux and signal ...
Two-dimensional buffer breaks substrate limit in III-nitrides epitaxy [0.03%]
二维缓冲层突破衬底限制实现高质量三族氮化物的外延生长
Yimeng Sang,Xiangming Xu,Ying Wu et al.
Yimeng Sang et al.
Expanding the diversity of substrate materials for the growth of single-crystalline films enables the heterointegration of electronic and optoelectronic devices in modern semiconductor industry. However, the substrate materials are restrict...
M6A-dependent RNA condensation underlies FUS autoregulation and can be harnessed for ALS therapy development [0.03%]
M6A依赖的RNA凝聚是FUS自调节的基础并可应用于ALS治疗开发
Wan-Ping Huang,Vedanth Kumar,Karen Yap et al.
Wan-Ping Huang et al.
Mutations in the FUS gene cause aggressive amyotrophic lateral sclerosis (ALS-FUS). Beyond mRNA, FUS generates partially processed transcripts retaining introns 6 and 7. We demonstrate that these FUSint6&7-RNA molecules form nuclear condens...
Tandem reaction-adsorption separation of perfluorinated cyclopropane/propane mixtures [0.03%]
全氟环丙烷/丙烷混合物的串联反应吸附分离法
Xinxin Li,Weiwei Zhang,Guang Miao et al.
Xinxin Li et al.
Separating perfluorinated cyclopropane/propane mixtures is critical yet challenging for sustainably producing high-purity perfluropropane in the advanced electronics industry. Conventional one-step adsorption separation methods lack proper ...
Starfish-inspired tube feet for temporary and switchable underwater adhesion and transportation [0.03%]
灵感来源于海星的管足的临时性以及可在水中切换的粘附和运输功能
Hyemin Lee,Yerin Ryu,Yejin Oh et al.
Hyemin Lee et al.
Temporary and reversible underwater adhesion is important for a number of robotic applications, including picking up objects, facilitating locomotion in confined environments, and attaching to surfaces during periods of observation. Here, w...
Benoît P Nicolet,Anouk P Jurgens,Kaspar Bresser et al.
Benoît P Nicolet et al.
Accurate protein expression in human immune cells is essential for appropriate cellular function. The mechanisms that define protein abundance are complex and are executed on transcriptional, posttranscriptional, and posttranslational level...