SCHEPHERD: A modular, programmable, direct current platform to control cell behavior [0.03%]
一种模块化可编程直流电平台 控制细胞行为
Yubin Lin,Jeremy S Yodh,Celeste Rodriguez et al.
Yubin Lin et al.
Spanning frogs, fish, and humans, direct current (dc) bioelectric cues play critical roles beyond neuromuscular function, such as modulating morphogenesis, immune response, and healing through electrotaxis-electrically directed cell migrati...
Bioinspired architected catalyst for efficient water purification: Bridging reactivity, reusability, and catalytic component utilization [0.03%]
一种用于高效水净化的仿生架构催化剂：活性、回收性和催化组分利用之间的平衡关系
Xirui Zhou,Songyan Zhang,Hanzheng Xing et al.
Xirui Zhou et al.
Achieving highly efficient water purification remains a formidable challenge due to intricate coupling among catalytic efficiency, mechanical robustness, and mass transport. Here, we create a bioinspired architected catalyst featuring micro...
Localized immunomodulation with cytokine-producing cells to mitigate foreign body responses in rodents and a nonhuman primate [0.03%]
采用细胞局部免疫调节以减轻啮齿类和非人灵长类动物的异物反应
Boram Kim,Dilrasbonu Vohidova,Amanda Nash et al.
Boram Kim et al.
The efficacy of cell-based therapeutics is often compromised by host immune recognition of implanted cells and biomaterials, resulting in fibrotic encapsulation and loss of function. Here, we address this challenge with an immunomodulatory ...
Dual-parameter chiral detection at the single-particle level enabled by surface cosine waves [0.03%]
表面余弦波实现单颗粒双参数手性检测
Shuangshuang Wang,Fengxia Wu,Wenxin Niu et al.
Shuangshuang Wang et al.
Accurately probing optical chirality at the single-particle level is essential for chiral molecular sensing, quantum optics, and enantioselective nanophotonic technologies. However, conventional chiroptical techniques rely on ensemble-avera...
Skeletal muscle H3K18 lactylation inhibits hepatic gluconeogenesis through IL-6 mediated interorgan communication [0.03%]
骨骼肌H3K18乳酸化通过IL-6介导的器官间交流抑制肝脏糖异生作用
Yu Wang,Feijie Wang,Yujie Sun et al.
Yu Wang et al.
The mechanisms underlying the dynamic interplay between skeletal muscle and systemic glucose homeostasis in type 2 diabetes remain elusive. Increased lactate level has long been noticed in diabetes, however, whether the elevated lactate is ...
Mid-infrared long-range surface polaritons in two-dimensional van der Waals materials [0.03%]
二维范德华材料中的中红外长程表面极化激元
Mingsong Wang,Shixiong Yin,Saroj Chand et al.
Mingsong Wang et al.
The discovery of graphene plasmons (GPs) and hyperbolic phonon polaritons (HPhPs) in two-dimensional (2D) van der Waals (vdW) materials has enabled extreme light confinement and enhanced light-matter interactions, holding the promise for mi...
Assembly-formed bioorthogonal chimeric artificial receptors enable high-contrast fluorescence imaging of tumors [0.03%]
基于组装的生物正交杂合型人工受体用于高对比度肿瘤荧光成像
Jianli Zuo,Yuxi Tan,Zhaode Mu et al.
Jianli Zuo et al.
Conventional receptor-targeted fluorescent probes have shown promise in tumor imaging, yet achieving a high tumor-to-normal (T/N) tissue ratio in vivo remains challenging due to limited biomarker density on tumor cell membranes. Here, we pr...
Sharp nanothorn-equipped ionogel microrobots for targeted periodontitis therapy [0.03%]
用于牙周炎靶向治疗的带有纳米棘轮装备的离子凝胶微机器人
Dongqing He,Zhaolei Zou,Dongdong Jin et al.
Dongqing He et al.
Periodontitis necessitates targeted therapy due to its high prevalence, progressive tissue destruction, and systemic disease links. Conventional mechanical debridement and pharmacological treatments are limited by complex periodontal barrie...
Early fate diversification of radial glial progenitors during corticogenesis [0.03%]
皮层发生过程中放射状胶质细胞系原早期命运分化
Irene Varela-Martínez,Ana Villalba,Jorge García-Marqués et al.
Irene Varela-Martínez et al.
Radial glial progenitors (RGPs) generate all projection neurons (PNs) in the cerebral cortex through incompletely understood processes. We combined Mosaic Analysis with Double Markers at embryonic stages (E)12.5 and E13.5 with early postnat...
Hybrid spatial organization and evidence for magnitude-independent neural coding of linguistic information during sentence production [0.03%]
混合空间组织以及句法产生过程中语言信息量无关的神经编码的证据
Adam M Morgan,Orrin Devinsky,Werner K Doyle et al.
Adam M Morgan et al.
Humans are the only species with the ability to systematically combine words to convey an unbounded number of complex meanings. This process is guided by combinatorial processes whose underlying neural mechanisms remain obscured by inherent...