Microalgae empower skeletal muscle via increased force production and viability [0.03%]
微藻通过增加肌肉力量和存活率增强骨骼肌
Xiang Wang,Claire Schirmer,Elena Totter et al.
Xiang Wang et al.
Engineered skeletal muscle holds potential for tissue engineering and biohybrid robotics applications. However, current strategies face challenges in enhancing force generation while maintaining stability and scalability of the muscle, larg...
Adaptive reward representations integrate expected uncertainty signals in orbitofrontal cortex [0.03%]
适应性奖励表达在眶额皮层中整合预期不确定性信号
Qianru Zhang,Jingfeng Zhou
Qianru Zhang
Incorporating expected uncertainty into reward evaluation is critical for adaptive learning and behavior. The orbitofrontal cortex (OFC) represents reward attributes, such as delay and magnitude, alongside expected uncertainties about upcom...
Pd@PdBO x heterostructure with strong electronic interaction to promote C─H bond activation for glycerol oxidation reaction [0.03%]
具有强电子相互作用的Pd@PdBO x 异质结构促进C-H键活化用于甘油氧化反应
Zhenyu Li,Kunhong Jiang,Yue Yang et al.
Zhenyu Li et al.
Glycerol oxidation reaction (GOR) represents an economical pathway for transforming renewable feedstock to value-added chemicals. However, the inertness of C(sp3)─H bonds of glycerol and intermediates results in the high energy barrier of ...
NRBP1 and TSC22D proteins affect distal convoluted tubule physiology through modulation of the WNK pathway [0.03%]
NRBP1 和 TSC22D 家族蛋白通过调节WNK途径影响远曲小管生理功能
Germán Magaña-Ávila,Héctor Carbajal-Contreras,Ramchandra V Amnekar et al.
Germán Magaña-Ávila et al.
The with-no-lysine (K) (WNK) kinases regulate processes such as cell volume and epithelial ion transport through the modulation of cation chloride cotransporters such as the NaCl cotransporter (NCC) present in the distal convoluted tubule (...
Taylor E Greenwood,Brian Elder,Md Nahid Hasan et al.
Taylor E Greenwood et al.
The wireless actuation of magnetic soft architectures can enable complex functionalities important in biomedicine and soft robotics. However, transforming and maintaining a device's desired geometry without a sustained energy input remains ...
Robert K Katzschmann,Thomas J K Buchner
Robert K Katzschmann
Enabling an ultraefficient lithium-selective construction through electric field-assisted ion control [0.03%]
通过电场调控离子实现超高锂分离选择性 конструктивности
Yan Zhao,Xue Yan,Lei Xia et al.
Yan Zhao et al.
Membranes with precise ion transport behaviors are regarded as an alternative for lithium (Li) extraction from water streams. Current membranes demonstrate limited viability due to the lack of efficient Li+-selective architectures. We propo...
Shuai-Peng Chen,Jiajia Zhang,Qi-Xiang Cai et al.
Shuai-Peng Chen et al.
Construction of artificial microscale helical superstructures holds great significance for understanding hierarchical evolution of chiral architectures in nature. However, fabricating microscale helical superstructures from metal clusters r...
Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing [0.03%]
通过CRISPR介导的DNA甲基化编辑调控免疫细胞命运和炎症反应
Gemma Valcárcel,Aleksey Lazarenkov,Anna V López-Rubio et al.
Gemma Valcárcel et al.
Immune cell differentiation and activation are associated with widespread DNA methylation changes; however, the causal relationship between these changes and their impact in shaping cell fate decisions still needs to be fully elucidated. He...
A Notch signal required for a morphological novelty in Drosophila has antecedent functions in genital disc eversion [0.03%]
notch信号在果蝇形态新颖性形成中的作用及其在生殖盘外翻过程中的先前功能研究
Donya N Shodja,William J Glassford,Gavin Rice et al.
Donya N Shodja et al.
The origin of morphological novelties has long fascinated biologists. Signaling pathways play important roles in the formation of novelties; however, the history of how they become integrated into new developmental programs remains unclear....