Structural mechanism of histone H2A.Z exchange by human SRCAP-CFDP1 holoenzyme
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The conserved yeast SWR1 and human SRCAP chromatin remodeling complexes catalyze exchange of nucleosomal histone H2A for H2A.Z, but the underlying mechanism has remained obscure. Here, we show that histone exchange by SRCAP requires the transient activator CFD... ...