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期刊名:Cell

缩写:CELL

ISSN:0092-8674

e-ISSN:1097-4172

IF/分区:42.5/Q1

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共收录本刊相关文章索引9608
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Andrew Murley,Ann Catherine Popovici,Xiwen Sophie Hu et al. Andrew Murley et al.
To maintain tissue homeostasis, many cells reside in a quiescent state until prompted to divide. The reactivation of quiescent cells is perturbed with aging and may underlie declining tissue homeostasis and resiliency. The unfolded protein ...
Erik Malmström,Lars Malmström,Simon Hauri et al. Erik Malmström et al.
The plasma proteome is maintained by the influx and efflux of proteins from surrounding organs and cells. To quantify the extent to which different organs and cells impact the plasma proteome in healthy and diseased conditions, we developed...
Huanhuan Li,Minh C Pham,Jinfeng Teng et al. Huanhuan Li et al.
Skeletal muscle contraction is triggered by acetylcholine (ACh) binding to its ionotropic receptors (AChRs) at neuromuscular junctions. In myasthenia gravis (MG), autoantibodies target AChRs, disrupting neurotransmission and causing muscle ...
Yunjin Lee,Tomoe Ishikawa,Hyeseung Lee et al. Yunjin Lee et al.
Cytokines interact with their receptor complexes to orchestrate diverse processes-from immune responses to behavioral modulation. Interleukin-17A (IL-17A) mediates protective immune responses by binding to IL-17 receptor A (IL-17RA) and IL-...
Byeongjun Lee,Jeong-Tae Kwon,Yire Jeong et al. Byeongjun Lee et al.
Patients with autoimmune or infectious diseases can develop persistent mood alterations after inflammatory episodes. Peripheral immune molecules, like cytokines, can influence behavioral and internal states, yet their impact on the function...
Zhisheng Wu,Yiheng Wang,Wei-Wei Chen et al. Zhisheng Wu et al.
Microglia, essential in the central nervous system (CNS), were historically considered absent from the peripheral nervous system (PNS). Here, we show a PNS-resident macrophage population that shares transcriptomic and epigenetic profiles as...
Shogo Soma,Norihito Hayatsu,Kengo Nomura et al. Shogo Soma et al.
Neural reflexes to chemicals in the throat protect the airway from aspiration and infection. Mechanistic understanding of these reflexes remains premature, exemplified by chronic cough-a sensitized cough reflex-being a prevalent unmet clini...
Menghan Liu,Sydney B Blattman,Mai Takahashi et al. Menghan Liu et al.
Despite the fundamental importance of gut microbes, the genetic basis of their colonization remains largely unexplored. Here, by applying cross-species genotype-habitat association at the tree-of-life scale, we identify conserved microbial ...
Xiaoyi Fan,Wanyu Li,Jessica Oros et al. Xiaoyi Fan et al.
Western equine encephalitis virus (WEEV) is an arbovirus that historically caused large outbreaks of encephalitis throughout the Americas. WEEV binds protocadherin 10 (PCDH10) as a receptor, and highly virulent ancestral WEEV strains also b...
Saravanan Raju,Sathvik Palakurty,Alan Sariol et al. Saravanan Raju et al.
The structural basis for shifts in receptor usage remains poorly understood despite the implications for virus adaptation and emergence. Western equine encephalitis virus (WEEV) strains exhibit different patterns of engagement for two of th...