Strategies for Enantioselective, Cascade, Valorizing, and Expanded Heterocyclic Piancatelli Rearrangements [0.03%]
enantselective、级联、增值和扩展的杂环Piancatelli重排策略
A Talim G K,Michael Kizirian,Elias Picazo
A Talim G K
The Piancatelli rearrangement of 2-furylcarbinols has become a versatile platform for the rapid assembly of densely functionalized cyclopentenones from renewable furan feedstocks. This Perspective highlights recent advances in four key dire...
An Axially Chiral Pyridyno-allenophane in a 2:1 Edge-to-Face Silver(I) Sandwich Complex: Synthesis and Structural Characterization [0.03%]
轴手性吡啶基烯丙烷与边缘-面银(I)金属夹化合物：合成及结构表征
Jonathan Álvarez-García,María Magdalena Cid
Jonathan Álvarez-García
We synthesized and characterized silver-(I) complexes featuring chiral pyridyno-allenophanesa class of cyclophanes integrating pyridine, alkyne, and allene units within a macrocyclic framework. X-ray diffraction revealed a 1:1 (ligand:met...
A Low-Potential π‑Extended Viologen Electron Donor Results in Increased H2 Production by Cp I [FeFe]-Hydrogenase [0.03%]
一种低电势π-延伸的ビログエン电子供体可提高Cp I [FeFe]-氢化酶产氢量
Nils Ostermann,Sophie Webb,Andrea Do Nascimento Henriques et al.
Nils Ostermann et al.
[FeFe]-hydrogenases are known for their exceptional dihydrogen production activity, which opens a pathway to green hydrogen formation. To achieve the high turnover numbers found in natural environments, researchers aim to mimic biological e...
High-Yield Room-Temperature Aryl 211At Radiolabeling via Redox-Activated Column-Shipped 211At [0.03%]
一种新型高产室温银柱运送砹-211交换法及其与芳香化合物的氧化偶联方法
Jehan S Perera,Jennifer M Pyles,Adrianna L Orsi et al.
Jehan S Perera et al.
Efficient late-stage formation of aryl-211At bonds is relevant to expanding the scope of targeted α-therapy radiopharmaceuticals. In this work, a catalyst-enabled astatodeboronation approach is evaluated using wet chemically regenerated 21...
Regioisomeric Control of Chemiexcitation Efficiency in Lophine Silylperoxides through Reaction-Path Topology and Excited-State Accessibility [0.03%]
洛芬烷基硅氧
Diego Ulysses Melo,Andreia Boaro,Roberta Albino Dos Reis et al.
Diego Ulysses Melo et al.
This study investigates the chemiluminescence (CL) of silylperoxides derived from lophines and their associated high-energy intermediates (HEIs), specifically 1,2-dioxetanes. Three regioisomeric silylperoxides (D1-3), differing in the posit...
Pursuing the Red-Shift in GlycoporphyrinsA New Synthetic Approach toward Glycoconjugates from the meso-Tetraethynylporphyrin Scaffold [0.03%]
从meso-四乙炔基卟啉支架追求糖代卟啉的合成新方法
Jakub Mitrzak,Maciej Malinowski
Jakub Mitrzak
Photodynamic therapy is a promising approach to anticancer treatment. For further development of this technique, new photosensitizers that better meet biological criteria are highly desired. Glycoporphyrins are considered more than favorabl...
Planar Chirality Directs Enantiospecific Diastereoselectivity in Isocyanide-Based Multicomponent Reactions [0.03%]
平面手性指引异腈基多组分反应的对映专一的非对映选择性
Michael Kapsalis,Michael Fragkiadakis,Iakovos Konstantaras et al.
Michael Kapsalis et al.
Stereochemical control in isocyanide-based multicomponent reactions (IMCRs) remains a fundamental challenge, particularly in substrate-controlled variants. Here we show that planar chirality embedded within [2.2]-paracyclophane scaffolds en...
Diastereoselective Synthesis of α‑Fluoro-γ-lactams via Difluorocarbene-Triggered Cyclization and Rearrangement [0.03%]
通过双氟碳烯触发的环化和重排实现α-氟-γ-内酰胺的非对映选择性合成
Maryam Jabbarpoor,Yanmei Li,Alex Akhundov et al.
Maryam Jabbarpoor et al.
We report a difluorocarbene-enabled, diastereoselective synthesis of α-fluoro-γ-lactams from readily accessible β-aminoketones and inexpensive, commercially available ethyl bromodifluoroacetate (EBDFA). Compared to established routes to ...
α‑Fluoronitroalkenes as Fluorinated Building Blocks: Solvent-Controlled Functionalization with Hydrazones [0.03%]
溶剂控制的杂环化合物与氟化硝基烯烃反应构筑C-F及C-N键
Matthew A Saucier,Hamdan Alrefaei,Peggy A McCluggage et al.
Matthew A Saucier et al.
While α-fluoronitroalkenes have been widely explored in annulation and cycloaddition chemistry, controlled intermolecular C-N bond formation through conjugate addition remains largely undeveloped. Moreover, solvent-controlled divergence be...
Gallylene-Mediated C-C Bond Activation of Diphenylcyclopropenone and Chalcogen Atom Insertion into a Ga-C Bond [0.03%]
环戊二烯酮的C-C键活化及Ga-C键的杂原子插入反应生成多环[10]芳烃类化合物
Nijito Mukai,Sota Iwasaki,Takuya Kodama et al.
Nijito Mukai et al.
We report the synthesis and structural characterization of a gallacyclobutenone. The gallacyclobutenone was synthesized via C-C bond oxidative addition of cyclopropenone to a Ga-(I) species bearing a phenalenyl-based bidentate ligand. Densi...