Loss of tricellular tight junction tricellulin leads to hyposalivation in Sjögren's syndrome [0.03%]
Sjögren综合征中三细胞紧密连接蛋白tricellulin的丢失导致低唾液分泌量
Xiangdi Mao,Haibing Li,Sainan Min et al.
Xiangdi Mao et al.
Tricellulin, a key tricellular tight junction (TJ) protein, is essential for maintaining the barrier integrity of acinar epithelia against macromolecular passage in salivary glands. This study aims to explore the role and regulatory mechani...
Administration of Porphyromonas gingivalis in pregnant mice enhances glycolysis and histone lactylation/ADAM17 leading to cleft palate in offspring [0.03%]
怀孕小鼠中Porphyromonas gingivalis的管理增强糖酵解和组蛋白乳酸化/ADAM17导致后代唇裂腭裂
Xige Zhao,Xiaoyu Zheng,Yijia Wang et al.
Xige Zhao et al.
Periodontal disease is a risk factor for many systemic diseases such as Alzheimer's disease and adverse pregnancy outcomes. Cleft palate (CP), the most common congenital craniofacial defect, has a multifaceted etiology influenced by complex...
Expert consensus on the clinical strategies for orthodontic treatment with clear aligners [0.03%]
透明对齐器矫正治疗的临床策略专家共识
Yan Wang,Hu Long,Zhihe Zhao et al.
Yan Wang et al.
Clear aligner treatment is a novel technique in current orthodontic practice. Distinct from traditional fixed orthodontic appliances, clear aligners have different material features and biomechanical characteristics and treatment efficienci...
Evolution of temporomandibular joint reconstruction: from autologous tissue transplantation to alloplastic joint replacement [0.03%]
颞下颌关节重建的演变：从自体组织移植到异体植入物置换
Hanghang Liu,Liwei Huang,Shibo Liu et al.
Hanghang Liu et al.
The reconstruction of the temporomandibular joint presents a multifaceted clinical challenge in the realm of head and neck surgery, underscored by its relatively infrequent occurrence and the lack of comprehensive clinical guidelines. This ...
Zhengmei Lin,Dingming Huang,Shuheng Huang et al.
Zhengmei Lin et al.
Intentional tooth replantation (ITR) is an advanced treatment modality and the procedure of last resort for preserving teeth with inaccessible endodontic or resorptive lesions. ITR is defined as the deliberate extraction of a tooth; evaluat...
Expert consensus on the prevention and treatment of enamel demineralization in orthodontic treatment [0.03%]
牙齿矫正治疗中釉质脱矿的预防和治疗专家共识
Lunguo Xia,Chenchen Zhou,Peng Mei et al.
Lunguo Xia et al.
Enamel demineralization, the formation of white spot lesions, is a common issue in clinical orthodontic treatment. The appearance of white spot lesions not only affects the texture and health of dental hard tissues but also impacts the heal...
Porphyromonas gingivalis potentiates stem-like properties of oral squamous cell carcinoma by modulating SCD1-dependent lipid synthesis via NOD1/KLF5 axis [0.03%]
口腔鳞状细胞癌中Porphyromonas gingivalis通过NOD1/KLF5轴调节SCD1依赖的脂质合成增强干细胞样特性
Wenli Zang,Fengxue Geng,Junchao Liu et al.
Wenli Zang et al.
Cancer stem cells (CSCs) are widely acknowledged as primary mediators to the initiation and progression of tumors. The association between microbial infection and cancer stemness has garnered considerable scholarly interest in recent years....
Circadian disruption by simulated shift work aggravates periodontitis via orchestrating BMAL1 and GSDMD-mediated pyroptosis [0.03%]
模拟轮班工作引起的昼夜节律紊乱通过调节BMAL1和GSDMD介导的焦亡加重牙周炎
Yazheng Wang,Rui Li,Qingyuan Ye et al.
Yazheng Wang et al.
Approximately 20% to 30% of the global workforce is engaged in shift work. As a significant cause of circadian disruption, shift work is closely associated with an increased risk for periodontitis. Nevertheless, how shift work-related circa...
Emerging roles of extracellular vesicles in oral and maxillofacial areas [0.03%]
口腔和颌面部区域的细胞外囊泡的作用机制及其新兴作用
Qianting Wang,Jiayu Sun,Haci Jiang et al.
Qianting Wang et al.
The oral and maxillofacial region is a highly complex area composed of multiple tissue types and bears various critical functions of the human body. Diseases in this region pose significant diagnostic and management challenges; therefore, e...
Jianfei Tang,Junjie Liu,Zekun Zhou et al.
Jianfei Tang et al.
Oral submucous fibrosis (OSF), characterized by excessive deposition of extracellular matrix (ECM) that causes oral mucosal tissue sclerosis, and even cancer transformation, is a chronic, progressive fibrosis disease. However, despite some ...