Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation [0.03%]
成纤维细胞衍生的补体C3通过促进巨噬细胞M1极化和破骨细胞分化来促进实验性牙周炎的发展
Feilong Ren,Shize Zheng,Huanyu Luo et al.
Feilong Ren et al.
Complement C3 plays a critical role in periodontitis. However, its source, role and underlying mechanisms remain unclear. In our study, by analyzing single-cell sequencing data from mouse model of periodontitis, we identified that C3 is pri...
Programmed death-ligand 1 regulates ameloblastoma growth and recurrence [0.03%]
程序性死亡配体1调节成釉细胞瘤的生长和复发
Linzhou Zhang,Hao Lin,Jiajie Liang et al.
Linzhou Zhang et al.
Tumor cell-intrinsic programmed death-ligand 1 (PD-L1) signals mediate tumor initiation, progression and metastasis, but their effects in ameloblastoma (AM) have not been reported. In this comprehensive study, we observed marked upregulatio...
Expert consensus on orthodontic treatment of patients with periodontal disease [0.03%]
牙周病患者的正畸治疗专家共识
Wenjie Zhong,Chenchen Zhou,Yuanyuan Yin et al.
Wenjie Zhong et al.
Patients with periodontal disease often require combined periodontal-orthodontic interventions to restore periodontal health, function, and aesthetics, ensuring both patient satisfaction and long-term stability. Managing these patients invo...
Exploring the mechanical and biological interplay in the periodontal ligament [0.03%]
探究牙周膜中的机械与生物相互作用
Xinyu Wen,Fang Pei,Ying Jin et al.
Xinyu Wen et al.
The periodontal ligament (PDL) plays a crucial role in transmitting and dispersing occlusal force, acting as mechanoreceptor for muscle activity during chewing, as well as mediating orthodontic tooth movement. It transforms mechanical stimu...
Xin Zhou,Si Chen,Chenchen Zhou et al.
Xin Zhou et al.
The prevalence of Class III malocclusion varies among different countries and regions. The populations from Southeast Asian countries (Chinese and Malaysian) showed the highest prevalence rate of 15.8%, which can seriously affect oral funct...
Expert consensus on imaging diagnosis and analysis of early correction of childhood malocclusion [0.03%]
儿童期错
Zitong Lin,Chenchen Zhou,Ziyang Hu et al.
Zitong Lin et al.
Early correction of childhood malocclusion is timely managing morphological, structural, and functional abnormalities at different dentomaxillofacial developmental stages. The selection of appropriate imaging examination and comprehensive r...
Macrophage ATF6 accelerates corticotomy-assisted orthodontic tooth movement through promoting Tnfα transcription [0.03%]
巨噬细胞的ATF6通过促进Tnfα转录来加速颌面切开辅助正畸牙齿移动
Zhichun Jin,Hao Xu,Weiye Zhao et al.
Zhichun Jin et al.
Corticotomy is a clinical procedure to accelerate orthodontic tooth movement characterized by the regional acceleratory phenomenon (RAP). Despite its therapeutic effects, the surgical risk and unclear mechanism hamper the clinical applicati...
Abnormal collagen deposition mediated by cartilage oligomeric matrix protein in the pathogenesis of oral submucous fibrosis [0.03%]
软骨寡聚基质蛋白在口腔黏膜下纤维化发病过程中介导的胶原异常沉积
Yafei Xiong,Xuechun Li,Bincan Sun et al.
Yafei Xiong et al.
Abnormal accumulation of collagen fibrils is a hallmark feature of oral submucous fibrosis (OSF). However, the precise characteristics and underlying mechanisms remain unclear, impeding the advancement of potential therapeutic approaches. H...
Author Correction: LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma [0.03%]
作者更正：LIMP-2通过促进咽颈鳞状细胞癌自噬诱导的GSK3β降解增强癌症干细胞特性
Yuantong Liu,Shujin Li,Shuo Wang et al.
Yuantong Liu et al.
Published Erratum
International journal of oral science. 2025 Mar 28;17(1):26. DOI:10.1038/s41368-025-00358-8 2025
Role and mechanisms of histone methylation in osteogenic/odontogenic differentiation of dental mesenchymal stem cells [0.03%]
组蛋白甲基化在牙髓间充质干细胞成骨/成牙本质分化中的作用和机制
Meijun Hu,Zhipeng Fan
Meijun Hu
Dental mesenchymal stem cells (DMSCs) are pivotal for tooth development and periodontal tissue health and play an important role in tissue engineering and regenerative medicine because of their multidirectional differentiation potential and...