Paras Ahmad,Nathan Estrin,Nima Farshidfar et al.
Paras Ahmad et al.
Mesenchymal stem cells are highly regarded for their potential in tissue repair and regenerative medicine due to their multipotency and self-renewal abilities. Recently, mesenchymal stem cells have been redefined as "medical signaling cells...
Platelet methyltransferase-like protein 4-mediated mitochondrial DNA metabolic disorder exacerbates oral mucosal immunopathology in hypoxia [0.03%]
血红素调节的血小板甲基转移酶样蛋白4介导的线粒体DNA代谢障碍加重缺氧相关口腔黏膜免疫病理损伤
Yina Zhu,Meichen Wan,Yutong Fu et al.
Yina Zhu et al.
Hypoxemia is a common pathological state characterized by low oxygen saturation in the blood. This condition compromises mucosal barrier integrity particularly in the gut and oral cavity. However, the mechanisms underlying this association ...
Identification of a Fusobacterial RNA-binding protein involved in host small RNA-mediated growth inhibition [0.03%]
鉴定出一种参与宿主小RNA介导的生长抑制的佛氏菌RNA结合蛋白
Puting Dong,Mengdi Yang,Jie Hu et al.
Puting Dong et al.
Host-derived small RNAs are emerging as critical regulators in the dynamic interactions between host tissues and the microbiome, with implications for microbial pathogenesis and host defense. Among these, transfer RNA-derived small RNAs (ts...
Succinate modulates oral dysbiosis and inflammation through a succinate receptor 1 dependent mechanism in aged mice [0.03%]
琥珀酸通过琥珀酸受体1依赖机制调节老年小鼠口腔菌群失调和炎症反应
Fangxi Xu,Yuqi Guo,Scott C Thomas et al.
Fangxi Xu et al.
Aging involves the accumulation of various forms of molecular and cellular damage over time. Key features of aging, such as mitochondrial dysfunction, dysbiosis, and oxidative stress, are closely linked and largely driven by inflammation. T...
Expert consensus on management of instrument separation in root canal therapy [0.03%]
根管治疗器械分离的处理专家共识
Yi Fan,Yuan Gao,Xiangzhu Wang et al.
Yi Fan et al.
Instrument separation is a critical complication during root canal therapy, impacting treatment success and long-term tooth preservation. The etiology of instrument separation is multifactorial, involving the intricate anatomy of the root c...
Functional and distinct roles of Piezo2-mediated mechanotransduction in dental primary afferent neurons [0.03%]
牙科初级感觉神经元中Piezo2介导的机械转导的功能和独特作用
Pa Reum Lee,Kihwan Lee,Ji Min Park et al.
Pa Reum Lee et al.
Piezo2, a mechanosensitive ion channel, serves as a crucial mechanotransducer in dental primary afferent (DPA) neurons and is potentially involved in hypersensitivity to mild mechanical irritations observed in dental patients. Given Piezo2'...
The research progress on periodontitis by the National Natural Science Foundation of China [0.03%]
我国国家自然科学基金资助的牙周病学研究进展
Liang Xie,Qian Chen,Hao Xu et al.
Liang Xie et al.
Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in Chi...
Physiologically relevant coculture model for oral microbial-host interactions [0.03%]
口腔微生物-宿主互作的生理相关共培养模型
Zeyang Pang,Nicole M Cady,Lujia Cen et al.
Zeyang Pang et al.
Understanding microbial-host interactions in the oral cavity is essential for elucidating oral disease pathogenesis and its systemic implications. In vitro bacteria-host cell coculture models have enabled fundamental studies to characterize...
Author Correction: Organoids in the oral and maxillofacial region: present and future [0.03%]
作者更正：口腔和颌面部类器官的现状与未来
Yufei Wu,Xiang Li,Hanzhe Liu et al.
Yufei Wu et al.
Published Erratum
International journal of oral science. 2025 May 27;17(1):43. DOI:10.1038/s41368-025-00377-5 2025
Osteomodulin modulates the inflammatory responses via the interleukin-1 receptor 1/nuclear factor-κB signaling pathway in dental pulpitis [0.03%]
骨模素通过白细胞介素-1受体1/核因子-κB信号途径调节牙髓炎的炎症反应
Yueyi Yang,Xuchen Hu,Meiling Jing et al.
Yueyi Yang et al.
Pulpitis is a common infective oral disease in clinical situations. The regulatory mechanisms of immune defense in pulpitis are still being investigated. Osteomodulin (OMD) is a small leucine-rich proteoglycan family member distributed in b...