Correction: Preventive effects of folic acid on Zika virus-associated poor pregnancy outcomes in immunocompromised mice [0.03%]
关于叶酸预防免疫缺陷小鼠寨卡病毒相关不良妊娠结局的作用的更正通知
Yogy Simanjuntak,Hui-Ying Ko,Yi-Ling Lee et al.
Yogy Simanjuntak et al.
[This corrects the article DOI: 10.1371/journal.ppat.1008521.]. Copyright: © 2026 Simanjuntak et al. This is an open access article distributed under th...
Published Erratum
PLoS pathogens. 2026 Jun 26;22(6):e1014363. DOI:10.1371/journal.ppat.1014363 2026
Co-inoculation with deformed wing virus and sacbrood virus affects viral and immune dynamics and synergistically increases honey bee mortality [0.03%]
同时感染翅膀畸形病毒和囊状幼虫病病毒会影响蜜蜂的病毒和免疫动态并协同增加蜜蜂死亡率
Alice Mélusine Durand,Eric Dubois,Anne Bonjour-Dalmon
Alice Mélusine Durand
Honey bees are commonly infected with viruses, including deformed wing virus (DWV-A and DWV-B) and sacbrood virus (SBV), which cause morphological symptoms and death in developing bees and primarily asymptomatic infections in adult bees. Co...
HSV-2 gC2 mRNA immunization in mice protects by producing antibodies that bind immune evasion epitopes [0.03%]
HSV-2 gC2 mRNA免疫接种可通过产生结合免疫逃逸表位的抗体来保护小鼠
Lauren M Hook,Tina M Cairns,Sita Awasthi et al.
Lauren M Hook et al.
Our vaccine candidate for genital herpes includes three immunogens involved in virus entry and immune evasion. HSV-2 glycoprotein C (gC2) is one of the immune evasion molecules that inhibits complement activation by binding C3b, and is the ...
O-GlcNAcylation licenses RNF166 to degrade the M protein of porcine coronaviruses [0.03%]
O-GlcNAc修饰使RNF166能够降解猪冠状病毒M蛋白
Runhui Qiu,Yucheng Zhang,Junwei Zhou et al.
Runhui Qiu et al.
Uridine diphosphate N‑acetylglucosamine (UDP‑GlcNAc) has often been overlooked because its source pathway contributes little to glucose flux. However, through O‑GlcNAcylation, even small fluctuations in UDP‑GlcNAc levels can be amplifie...
SUMOylation and ubiquitination reciprocally regulate SMCHD1 antiviral activity against herpes simplex virus 1 [0.03%]
SUMOylation和泛素化互为调节以对抗I型单纯疱疹病毒的SMCHD1抗病毒活性
Xuezhang Tian,Xinyue Wang,Shaowei Wang et al.
Xuezhang Tian et al.
Host restriction factors serve as intrinsic barriers against viral infection, and are frequently counteracted by viral antagonists. Previous studies, including our own, have identified SMCHD1 as a restriction factor that suppresses the repl...
Predictive value of PfEMP1 antibody profiles for the course of controlled human malaria infections [0.03%]
PfEMP1抗体谱型对控制人类疟疾感染进程的预测价值
Yannick D Höppner,Ralf Krumkamp,Hikaru Nagaoka et al.
Yannick D Höppner et al.
Antibody-mediated immunity directed against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important immune mechanism for protection against clinical malaria and control of parasitemia. Current studies on PfEMP1-based i...
RNA methyltransferase CMTR-1 inhibition activates a GATA transcription factor-mediated protective immune response [0.03%]
CMTR-1抑制激活GATA转录因子介导的保护性免疫反应
Annesha Ghosh,Jogender Singh
Annesha Ghosh
Organisms can activate innate immunity not only by detecting pathogens but also by sensing disturbances to essential cellular processes. Such damage-based surveillance provides a means to identify cellular disruptions that prime host immuni...
Obligatory intracellular bacterium Anaplasma phagocytophilum AnkA regulates actin dynamics and spatiotemporal bacterial release [0.03%]
细胞内义务菌安纳普劳玛噬菌体ANKA调节肌动蛋白动力学和时空细菌释放
Mingqun Lin,Nan Duan,Yasuko Rikihisa
Mingqun Lin
Anaplasma phagocytophilum is an obligatory intracellular bacterium that causes an emerging infectious disease, human granulocytic anaplasmosis. It undergoes a biphasic developmental cycle inside membrane-bound vacuoles within the host human...
Beyond resistance: Emerging methods to dissect drug responses in Leishmania [0.03%]
超越耐药性：解剖利什曼原虫药物反应的新方法
Beatriz Cristina Dias de Oliveira,Jorge Arias Del Angel,Nicole Herrmann May et al.
Beatriz Cristina Dias de Oliveira et al.
Treatment failure and relapse remain major challenges in leishmaniasis despite available chemotherapies. Historically, these outcomes have been interpreted through the lens of classical drug resistance driven by heritable genetic mutations....
Schistosoma japonicum histone acetyltransferase 1 (SjHAT1): A novel anti-schistosomal drug target [0.03%]
日本血吸虫组蛋白乙酰转移酶1（SjHAT1）：一种新型抗血吸虫病药物作用靶点
Jing Xu,Yu-Xin Wang,Ping Huang et al.
Jing Xu et al.
Schistosomiasis remains a critical global health issue, necessitating novel therapies due to emerging praziquantel resistance. We previously developed a patented praziquantel derivative, DW-3-15, which demonstrated potent broad-spectrum sch...