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O-GlcNAcylation licenses RNF166 to degrade the M protein of porcine coronaviruses

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Uridine diphosphate N‑acetylglucosamine (UDP‑GlcNAc) has often been overlooked because its source pathway contributes little to glucose flux. However, through O‑GlcNAcylation, even small fluctuations in UDP‑GlcNAc levels can be amplified to shape immune re... ...