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Schistosoma japonicum histone acetyltransferase 1 (SjHAT1): A novel anti-schistosomal drug target

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Schistosomiasis remains a critical global health issue, necessitating novel therapies due to emerging praziquantel resistance. We previously developed a patented praziquantel derivative, DW-3-15, which demonstrated potent broad-spectrum schistosomicidal activi... ...