Targeting RORγ to boost regulatory T cells and ameliorate diabetic retinopathy in mice [0.03%]
靶向RORγ以促进调节性T细胞的生成并改善小鼠糖尿病视网膜病变
Devy Deliyanti,Varaporn Suphapimol,Phoebe Ang et al.
Devy Deliyanti et al.
Diabetic retinopathy, a leading cause of blindness, features damage to the retinal vasculature, where T cell-mediated inflammation is increasingly recognised as an important contributor. Retinoic acid receptor-related orphan receptor gamma ...
Hepatocyte-specific MET deletion exacerbates acetaminophen-induced hepatotoxicity in mice [0.03%]
小鼠特异性MET肝细胞敲除加重四氯化碳致肝损伤病理学症状
Siddhi Jain,Ranjan Mukherjee,Gillian Williams et al.
Siddhi Jain et al.
Despite the well-known role of MET in liver regeneration following partial-hepatectomy (PHx), its role in the clinically-relevant acetaminophen (APAP)-induced liver injury (AILI) model remains unexplored. AILI markedly differs from PHx beca...
Periostin deletion reduces corneal opacity and the infiltration of immune cells [0.03%]
删除Periostin可降低角膜混浊和免疫细胞浸润水平
Hyemin Seong,Chieun Song,Mingyo Kim et al.
Hyemin Seong et al.
Corneal opacity resulting from corneal injury is a leading cause of blindness. The interaction of extracellular matrix (ECM) proteins, cytokines and immune cells induces corneal opacity after corneal injury. Periostin, which is secreted int...
The D2.B10-Dmdmdx/J mouse model of DMD exhibits a severe mitochondrial deficiency not observed in the C57BL/10ScSn-Dmdmdx/J mouse [0.03%]
D2背景的mdx小鼠表现出线粒体功能障碍而C57BL/10背景的mdx小鼠没有此现象
Jennifer A Tinklenberg,Jessica Sutton,Rebecca A Slick et al.
Jennifer A Tinklenberg et al.
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene resulting in dystrophin deficiency in skeletal/cardiac muscle and progressive loss of function. While the genetic causes of DMD have been thoroughly investigated, the ...
Decreased Glycolysis due to LDHA m6A methylation in Endometrium of endometriosis impairs its decidualization and contributes to related infertility [0.03%]
子宫内膜异位症中LDHA m6A甲基化导致糖酵解降低从而抑制蜕膜化并参与相关不孕发生
Ruiweng Weng,Yi Liu,Wenqian Xiong
Ruiweng Weng
Endometriosis-related infertility is a prevalent reproductive health concern of global significance. Functional abnormalities of the endometrium are increasingly recognized as a pivotal contributor to infertility in affected individuals. In...
The Gut Microbiome as a Possible Mediator in Autoimmunity and Cardiovascular Disease: Shared Pathways and Therapeutic Implications [0.03%]
肠道微生物组可能是自身免疫和心血管疾病共通发病机制的介导因素及治疗靶点
Marina M Bellet,Francesco Curcio,Luigi Frati et al.
Marina M Bellet et al.
This review explores the emerging role of the gut microbiome in bridging autoimmunity and cardiovascular diseases (CVDs). Dysbiosis, an imbalance in gut microbial composition, disrupts immune regulation, metabolic pathways, and vascular hea...
Retraction Notice to "Aberrant CD8+ T-Cell Responses and Memory Differentiation upon Viral Infection of an Ataxia-Telangiectasia Mouse Model Driven by Hyper-Activated Akt and mTORC1 Signaling" [Am J Pathol 178 (2011) 2740-2751] [0.03%]
关于“小脑萎缩性共济失调的小鼠模型病毒感染条件下CD8+T细胞的异常免疫反应和记忆分化是由Akt和mTORC1过度活化所导致”的撤稿声明[Am J Pathol 178 (2011) 2740-2751]
Anthony D D&#x;Souza,Ian A Parish,Sharen E McKay et al.
Anthony D D&#x;Souza et al.
Published Erratum
The American journal of pathology. 2025 Oct;195(10):1961. DOI:10.1016/j.ajpath.2025.08.002 2025
Correction [0.03%]
改正错误
From The American Journal of Pathology's Archives: Pioneering Studies on the Mechanisms of Metastatic Prostate Cancer [0.03%]
美国病理学杂志档案中的前列腺癌转移机制的开创性研究
Chris Albanese,Olga C Rodriguez
Chris Albanese