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Novel murine models of hematopoietic-endothelial crosstalk in JAK2V617F-associated cardiovascular disease

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Cardiovascular disease (CVD) is a major complication of JAK2V617F-positive myeloproliferative neoplasms (MPNs), yet the mechanisms linking mutant hematopoiesis to CVD remain incompletely understood. We developed three complementary murine models to delineate t... ...