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Bim inhibition ameliorates visual loss and promotes axon regeneration by upregulation of Drd1 expression

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This study evaluated the neuroprotective effects of inhibiting the pro-apoptotic molecule Bim (Bcl-2-interacting mediator of cell death) in retinal ganglion cells (RGCs). A mouse optic nerve crush (ONC) model was used to induce RGC degeneration. Bim expression... ...