Sampling representational plasticity of simple imagined movements across days enables long-term neuroprosthetic control [0.03%]
通过在多天内采样简单的想象运动的表征可塑性实现长期神经假肢控制
Nikhilesh Natraj,Sarah Seko,Reza Abiri et al.
Nikhilesh Natraj et al.
The nervous system needs to balance the stability of neural representations with plasticity. It is unclear what the representational stability of simple well-rehearsed actions is, particularly in humans, and their adaptability to new contex...
From big data and experimental models to clinical trials: Iterative strategies in microbiome research [0.03%]
从大数据和实验模型到临床试验：微生物组研究中的迭代策略
Sondra Turjeman,Tommaso Rozera,Eran Elinav et al.
Sondra Turjeman et al.
Microbiome research has expanded significantly in the last two decades, yet translating findings into clinical applications remains challenging. This perspective discusses the persistent issue of correlational studies in microbiome research...
Xiang Xiao,Jian Wang,Kang Ding
Xiang Xiao
Here, we introduce the Mariana Trench Environment and Ecology Research (MEER) project, which provides the first systematic view of the ecosystem in the hadal zone. ...
In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography [0.03%]
通过冷冻电子层析技术观察完整组织中copia逆转座子的细胞内结构和瞬间状态
Sven Klumpe,Kirsten A Senti,Florian Beck et al.
Sven Klumpe et al.
Long terminal repeat (LTR) retrotransposons belong to the transposable elements (TEs), autonomously replicating genetic elements that integrate into the host's genome. Among animals, Drosophila melanogaster serves as an important model orga...
CXCL12 drives natural variation in coronary artery anatomy across diverse populations [0.03%]
CXCL12驱动不同人群中冠状动脉解剖结构的自然变异
Pamela E Rios Coronado,Jiayan Zhou,Xiaochen Fan et al.
Pamela E Rios Coronado et al.
Coronary arteries have a specific branching pattern crucial for oxygenating heart muscle. Among humans, there is natural variation in coronary anatomy with respect to perfusion of the inferior/posterior left heart, which can branch from eit...
Ugne Klibaite,Tianqing Li,Diego Aldarondo et al.
Ugne Klibaite et al.
Social interaction is integral to animal behavior. However, lacking tools to describe it in quantitative and rigorous ways has limited our understanding of its structure, underlying principles, and the neuropsychiatric disorders, like autis...
Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization [0.03%]
利用IL-10R滞后性的细菌免疫疗法，实现吞噬逃逸和肿瘤免疫 revitalization
注：此处的"revitalization"直译为“恢复活力”，但在上下文中指的是增强或重新激活肿瘤免疫反应的意思。因此，“revitalization”被翻译为“免疫 revitalization”。为了使语句更加通顺和符合中文表达习惯，可以调整为：“利用IL-10R滞后性的细菌免疫疗法实现吞噬逃逸及肿瘤免疫恢复”。
Zhiguang Chang,Xuan Guo,Xuefei Li et al.
Zhiguang Chang et al.
Bacterial immunotherapy holds promising cancer-fighting potential. However, unlocking its power requires a mechanistic understanding of how bacteria both evade antimicrobial immune defenses and stimulate anti-tumor immune responses within t...
Xiaojie Qiu,Daniel Y Zhu,Yifan Lu et al.
Xiaojie Qiu et al.
Published Erratum
Cell. 2025 Mar 1:S0092-8674(25)00253-3. DOI:10.1016/j.cell.2025.02.026 2025
A deep learning strategy to identify cell types across species from high-density extracellular recordings [0.03%]
通过高密度细胞外记录跨物种识别细胞类型的深度学习策略
Maxime Beau,David J Herzfeld,Francisco Naveros et al.
Maxime Beau et al.
High-density probes allow electrophysiological recordings from many neurons simultaneously across entire brain circuits but fail to reveal cell type. Here, we develop a strategy to identify cell types from extracellular recordings in awake ...
HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy [0.03%]
HIF调节多种可翻译的内源性逆转录病毒：对癌症免疫治疗的意义
Qinqin Jiang,David A Braun,Karl R Clauser et al.
Qinqin Jiang et al.
Clear cell renal cell carcinoma (ccRCC), despite having a low mutational burden, is considered immunogenic because it occasionally undergoes spontaneous regressions and often responds to immunotherapies. The signature lesion in ccRCC is ina...