MT-125 inhibits non-muscle myosin IIA and IIB and prolongs survival in glioblastoma
{{output}}
Glioblastoma (GBM) is the most lethal of primary brain tumors. Here, we report our studies of MT-125, a small-molecule inhibitor of non-muscle myosin II. MT-125 has high brain penetrance and an excellent safety profile, blocks GBM invasion and cytokinesis, and... ...
