Characteristics Comparison and Functional Analysis of TLR5S in Two Mandarin Fish Species (Siniperca scherzeri and Siniperca chuatsi) [0.03%]
两种马口鱼（Siniperca scherzeri和Siniperca chuatsi）TLR5基因的特征比较及功能分析
Xinhai Zhu,Chencheng Hu,Liying Zhou et al.
Xinhai Zhu et al.
Toll-like receptor 5 (TLR5) is a key pattern-recognition receptor that senses bacterial flagellin, and teleosts typically possess both membrane-bound and soluble isoforms. To explore species-specific TLR5-mediated antibacterial responses in...
Aeromonas hydrophila induces mitophagy for intracellular survival through its secreted effectors in the splenic macrophages of grass carp (Ctenopharyngodon idella) [0.03%]
水产动物病原菌肠液青霉素通过分泌效应蛋白诱导线粒体自噬促进细菌胞内存活的新机制研究——以草鱼单核吞噬细胞为模型
Xiaoyu Ma,Rong Ye,Wansong Li et al.
Xiaoyu Ma et al.
Aeromonas hydrophila, a Gram-negative bacterium ubiquitously distributes in aquatic environments, represents a prevalent pathogenic threat to aquatic animals. The present study investigated how A. hydrophila induced mitophagy to promote its...
CcFTR54 restricts spring viremia of carp virus replication by promoting p62-mediated autophagic degradation of N protein [0.03%]
CCFRT54通过促进p62介导的N蛋白自噬降解限制鲤春病毒血症病毒复制
Rongrong Liu,Hongxia Gao,Xin Li et al.
Rongrong Liu et al.
The tripartite motif (TRIM) protein family represents one of the largest groups of E3 ubiquitin ligases and plays pivotal roles in host antiviral innate immunity. In teleost fish, finTRIM proteins (FTR) have undergone lineage-specific expan...
Dietary ferulic acid boosts the immunity and antioxidant activity of T lymphocytes in Nile tilapia (Oreochromis niloticus) challenged with Aeromonas hydrophila [0.03%]
dietary ferulic酸通过增强Nile罗非鱼（Oreochromis niloticus）中的T淋巴细胞的免疫力和抗氧化活性来对抗Aeromonas hydrophila挑战
Jiansong Zhang,Yuqing Yang,Jingwen Chang et al.
Jiansong Zhang et al.
Functional feed additives are increasingly incorporated into aquafeeds to improve growth performance, metabolic status, and overall health of farmed fish. However, their regulatory effects on adaptive immunity, particularly T cell-mediated ...
Dietary myo-inositol exerts pleiotropic effects on T cell activation, antioxidant defense and fatty acid metabolism to enhance anti-bacterial immunity in tilapia [0.03%]
饲喂肌醇对提高尼罗罗非鱼抗细菌免疫的影响及其作用机制研究
Zhichao Fang,Yuying Zheng,Minghui Zhang et al.
Zhichao Fang et al.
Bacterial diseases cause major economic losses in aquaculture, underscoring the need for feed additives that enhance fish immunity. Myo-inositol (MI), an essential nutrient for fish growth, possesses antioxidant and lipid-metabolism modulat...
Functional characterization of interferon-induced protein 44-like in Amphiprion clarkii: Expression profiles, immunomodulatory activity, and antiviral function [0.03%]
拟斑克氏安鼻鱼干扰素诱导蛋白44样蛋白的功能表征：表达谱、免疫调节活性和抗病毒功能
Yasara Kavindi Kodagoda,D C G Rodrigo,U P E Arachchi et al.
Yasara Kavindi Kodagoda et al.
Interferon-induced protein 44-like (IFI44L) is an interferon-stimulated gene (ISG) that plays a critical role in antiviral defense by modulating host innate immune responses. In this study, IFI44L homolog (AcIFI44L) was identified and funct...
Identification and functional study of CDK gene family in cell proliferation in the Chinese mitten crab (Eriocheirsinensis) [0.03%]
中国绒螯蟹（Eriosentissinensis）细胞增殖过程中CDK基因家族的鉴定及功能研究
Wen Zhang,Zifeng Wang,Chaohui Xu et al.
Wen Zhang et al.
CDK genes play crucial roles in key biological processes such as cell cycle progression and transcriptional regulation. However, the specific number of CDK gene family members in the Chinese mitten crab (Eriocheir sinensis) remained unclear...
Sampling conditions affect immune cell viability and function in the Mediterranean mussel (Mytilus galloprovincialis) [0.03%]
取样条件影响地中海贻贝壳层免疫细胞的存活和功能
Teresina De Iorio,Chiara Profico,Fabrizio Capoccioni et al.
Teresina De Iorio et al.
Farmed animal welfare is becoming a socially relevant issue. Several strategies have been developed to assess the welfare of farmed animals in vitro, including the evaluation of immune functions. The appropriate isolation of immune cells pl...
Expression and function of zebrafish carboxypeptidase A5 in neutrophils and mast cells [0.03%]
斑马鱼中性粒细胞和肥大细胞中羧肽酶A5的表达及其功能研究
Ziyan Wu,Yunjia Hu,Songen Xu et al.
Ziyan Wu et al.
Mast cells originate from mammalian myeloid hematopoiesis and exert a crucial role in inflammation and allergies. In recent years, studies have reported that carboxypeptidase A5 (cpa5) can serve as a marker for zebrafish mast cells. However...
Immunomodulatory and anti-apoptotic effects of heme oxygenase-1 in hypoxia stress of small yellow croaker (Larimichthys polyactis) [0.03%]
小黄鱼（Larimichthys polyactis）低氧应激下血红素加氧酶HO-1的免疫调节和抗凋亡效应
Yang Liu,Qiaoling Yang,Xuebin Zheng et al.
Yang Liu et al.
To clarify whether heme oxygenase-1 (HO-1) plays an immunomodulatory and anti-apoptotic role in hypoxia stress of small yellow croaker. In this study, histological observation, biochemical detection, gene expression detection, gene interfer...