The critical x[I/L]xbS motif in adaptor proteins, MAVS, MITA, and TRIF contributes to type I IFN production and antiviral immune response in fish
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Mammalian antiviral signaling adaptors, such as MAVS, MITA, and TRIF, have been shown to possess a conserved pLxIS motif (p, hydrophilic residue; L, leucine; x, any residue; I, isoleucine; S, serine, phosphorylation site), which has been identified as the key ... ...
