A comparative study of DEB-TACE alone and DEB-TACE combined with targeted therapy and immunotherapy in the treatment of intermediate-advanced hepatocellular carcinoma [0.03%]
单纯药物洗脱粒子载药肝动脉化疗栓塞术与联合靶向及免疫治疗在中期和晚期肝细胞癌中疗效的比较研究
Fangye Wu,Hui Zeng
Fangye Wu
Objective: The aim of the present study was to compare the efficacy and safety of drug‑eluting beads transarterial chemoembolization (DEB-TACE) with CalliSpheres® microspheres (CSM) combined with targeted therapy and im...
Clinical significance of concurrent TP53 mutations in KRAS-mutant invasive mucinous adenocarcinoma patients undergoing curative-intent lung surgery [0.03%]
KRAS突变型侵袭性黏液腺癌患者在接受治愈性肺手术时并发TP53突变的临床意义
Dong Woog Yoon,Soohyun Hwang,Boram Lee et al.
Dong Woog Yoon et al.
Background: Invasive mucinous adenocarcinoma (IMA) is genetically distinct from non-mucinous adenocarcinoma, commonly characterized by KRAS mutations. However, studies exploring molecular co-alterations alongside KRAS mut...
Investigating the quality of sexual function in women with genital cancers: A structural equation analysis approach [0.03%]
女性生殖系统癌症患者性功能质量状况及其影响因素的结构方程模型分析
Sara Moradi,Parvin Hassanzadeh,Mahsa Kahrobaie et al.
Sara Moradi et al.
Background: Genital cancers significantly impair women's quality of life, with sexual dysfunction as a common yet under-addressed issue. Most studies use univariate analyses and lack a comprehensive model of the multifact...
Racial/ethnic disparities in hepatocellular carcinoma treatment and survival: an analysis of the California Cancer Registry [0.03%]
基于加州癌症登记数据库的肝细胞癌治疗及生存结局种族差异分析研究
Daneng Li,Christiana Joy Crook,Ya-Han Zhang et al.
Daneng Li et al.
Background: Hepatocellular carcinoma is the third-leading cause of cancer-related death worldwide. In the United States, California has the highest hepatocellular carcinoma incidence burden and a high level of racial/ethn...
Assessing the pathogenicity of a variant of uncertain significance in the ALK gene in right-sided colon polyposis [0.03%]
ALK基因变异在右侧结肠息肉病致病性评估中的作用
Zeinab Aliyari Serej,Maryam Naghinejad,Sepideh Parvizpour et al.
Zeinab Aliyari Serej et al.
Colorectal cancer (CRC) is the third most common cancer worldwide. Generally, Familial Adenomatous Polyposis (FAP) accounts for about 1 % to 2 % of all colorectal cancer cases. Mutations in the APC gene, inherited in an autosomal dominant m...
A retrospective analysis of the efficacy and safety of immune combination therapy in driver gene-negative non-small cell lung cancer with brain metastases [0.03%]
驱动基因阴性伴脑转移非小细胞肺癌免疫联合治疗疗效及安全性的回顾性分析
Kuo Li,Bingxiang Wang,Shuaishuai Liu et al.
Kuo Li et al.
Purpose: Central nervous system metastases, significantly worsen the prognosis of driver gene-negative non-small cell lung cancer (NSCLC) patients. This study aims to evaluate the efficacy and safety of immunotherapy in d...
Clonal origins and divergent evolutionary relationships of synchronous multiple malignant neoplasms in gynecology revealed by next-generation sequencing [0.03%]
基于下一代测序技术揭示的妇科肿瘤的克隆起源及并行发展的异质性关系
Jindong Sheng,Jing Luan,Yujie Zhao et al.
Jindong Sheng et al.
Background: Synchronous multiple malignant neoplasms (SMMNs) in gynecology involving the ovary, endometrium, and cervix are rare and pose a significant diagnostic challenge when the primary lesion is unclear. ...
Photodynamic therapy with zinc phthalocyanine enhances cisplatin sensitivity of human muscle-invasive bladder cancer cells by downregulation of PI3K/AKT/mTOR signaling pathway [0.03%]
锌酞菁光动力疗法通过下调PI3K/AKT/mTOR信号通路增强顺铂对人膀胱癌细胞的敏感性
Fateme Mohammadnejad,Neda Rajabi,Mohammad Amin Doustvandi et al.
Fateme Mohammadnejad et al.
Cisplatin (CIS) is mainly used as a chemotherapeutic drug for bladder cancer (BLC). However, the total response of CIS-based chemotherapy in BLC remains unsatisfactory owing to the complex genomic differences, pathological subtypes, and dru...
Correlation between TTF-1 expression and EGFR mutations in moroccan lung adenocarcinoma: A prospective six-year study [0.03%]
TTF-1表达与摩洛哥肺腺癌EGFR突变的相关性：一项六年的前瞻性研究
Sara Boukansa,Ismail Mouhrach,Fatima El Agy et al.
Sara Boukansa et al.
Objective: Lung cancer is the second most common malignancy worldwide and remains a leading cause of cancer-related mortality. Identifying predictive biomarkers is essential to improve personalized treatment. This prospec...
Factors influencing the diagnostic basis in pancreatic cancer. A study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort [0.03%]
影响胰腺癌诊断依据的因素。一项欧洲癌症和营养前瞻性调查（EPIC）队列研究
Miquel Porta,José Pumarega,Àlex Giménez et al.
Miquel Porta et al.
Background and aims: Substantial differences have been reported in risk estimates for etiologic factors of pancreatic cancer among subjects with different degrees of diagnostic certainty. The aim of the study was to asses...