Assessing the pathogenicity of a variant of uncertain significance in the ALK gene in right-sided colon polyposis
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Colorectal cancer (CRC) is the third most common cancer worldwide. Generally, Familial Adenomatous Polyposis (FAP) accounts for about 1 % to 2 % of all colorectal cancer cases. Mutations in the APC gene, inherited in an autosomal dominant manner, and mutations... ...