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Photodynamic therapy with zinc phthalocyanine enhances cisplatin sensitivity of human muscle-invasive bladder cancer cells by downregulation of PI3K/AKT/mTOR signaling pathway

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Cisplatin (CIS) is mainly used as a chemotherapeutic drug for bladder cancer (BLC). However, the total response of CIS-based chemotherapy in BLC remains unsatisfactory owing to the complex genomic differences, pathological subtypes, and drug resistance. In BLC... ...