Antimicrobial resistance dynamics in Mycobacterium tuberculosis coinfection systems: A spatiotemporal strain analysis [0.03%]
结核分枝杆菌共感染系统的抗菌药物抗性动态变化：时空菌株分析
Jie Dai,Fanglin Zeng,Fengyue Hu et al.
Jie Dai et al.
Secondary pulmonary infections are crucial and pivotal contributing factors to clinical deterioration in patients with pulmonary tuberculosis. Research remains limited regarding the specific population and regional epidemiology of these sec...
Nutritional, Anti-inflammatory, and in-silico inhibitory Studies of Trametes versicolor (L.) Lloyd and Flammulina velutipes (Curtis) on HER2 breast cancer protein [0.03%]
营养、抗炎和计算机辅助抑制试验：Trametes versicolor（L.）Lloyd 和 Flammulina velutipes（Curtis）对 HER2 乳腺癌蛋白的作用研究
Osamudiame M Iyekekpolor,Okukwe C Obode,Abiodun H Adebayo
Osamudiame M Iyekekpolor
This study evaluated the phytochemical, nutritional, anti-inflammatory, and in-silico anticancer properties of T. versicolor and F. velutipes. Phytochemical screening revealed high levels of phenols, saponins, and flavonoids in both species...
Capsaicin responses in Drosophila: Exploring the possibility of establishing a new Non-TRPV1 model [0.03%]
辣椒素反应在果蝇中的研究：建立新的非瞬时受体电位香草素通道模型的可能性探索
Gerardo Flores-Iga,Mohankumar Amirthalingam,Carlos Lopez-Ortiz et al.
Gerardo Flores-Iga et al.
Capsaicin, the primary pungent compound in chili peppers, activates the heat-sensitive ion channel transient receptor potential vanilloid 1 (TRPV1) in mammals, eliciting the characteristic burning sensation. On the other hand, Drosophila me...
The miR-2110/ TRAF3 axis is associated with endothelial dysfunction and atherosclerosis in coronary heart disease [0.03%]
miR-2110/TRAF3轴与冠心病血管内皮功能障碍和动脉粥样硬化的关系
ThanhLoan Tran,Zhong-Yu Wang,Pei-Shan Li et al.
ThanhLoan Tran et al.
Coronary heart disease (CHD) is driven by endothelial dysfunction and chronic vascular inflammation. hsa-miR-2110 (miR-2110) has been associated with adverse cardiovascular outcomes, but its mechanistic role in CHD remains unclear. In this ...
Dose-dependent anxiolytic and antidepressant-like effects of chronic oxytocin in corticosterone-induced female mouse model of anxiety and depression [0.03%]
催产素在皮质酮诱导的焦虑抑郁模型小鼠中的剂量依赖性的抗焦虑和抗抑郁作用
Masayoshi Mori,Misaki Tamura,Norihiro Sumi et al.
Masayoshi Mori et al.
Oxytocin (OXT) has therapeutic effects on psychiatric disorders, such as anxiety and depression, in both animals and humans; however, an increasing number of OXT treatment studies have reported conflicting results. Although the effects of O...
Immunoinformatic-driven design of a multi-epitope vaccine against Helicobacter pylori [0.03%]
免疫信息学驱动的幽门螺旋杆菌多抗原表位疫苗设计
Nasim Rahimi-Farsi,Fatemeh Bostanian,Khadijeh Ahmadi et al.
Nasim Rahimi-Farsi et al.
Helicobacter pylori (H. pylori) is present in the gastric mucosa of approximately half of the global population and is classified as a definitive type I carcinogen. Developing a logical and effective vaccine against H. pylori remains a crit...
Comprehensive analysis of the deleterious nonsynonymous, non-coding SNPs and cancer variants of human aldo-keto reductase type 1 (AKR1C1) protein and their probable association with disease risk and progression: a computational study [0.03%]
人类醛酮还原酶类型1（AKR1C1）蛋白有害非同义、非编码SNP和癌症变异的全面分析及其与疾病风险和进展的可能关联：一项计算研究
Nurun Nahar Nila,Israt Dilruba Mishu,Zimam Mahmud et al.
Nurun Nahar Nila et al.
Aldo-keto reductase family 1 member C1 (AKR1C1) is a key enzyme involved in steroid hormone and xenobiotic metabolism and has been implicated in hormone-dependent cancers, chemoresistance, and inflammatory disorders. Genetic variation in AK...
Enhancement of prime editing by recruiting engineered or evolved components and implementing novel strategies [0.03%]
通过招募工程或进化组件和实施新型策略来增强prime编辑技术
Mobina Arabi,Farzaneh Alizadeh,Yasamin Yousefi et al.
Mobina Arabi et al.
Prime editing has recently gained attention for its promising potential in treating genetic disorders caused by different types of mutations. This method, based on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), has led ...
Monocyte chemoattractant protein-1 (MCP-1/CCL2) and matrix metalloproteinase-9 (MMP-9) as biomarkers of disease severity in COVID-19 patients [0.03%]
单核细胞趋化蛋白1(CCL2)和基质金属蛋白酶9(MMP-9)作为新冠肺炎病情严重程度生物标志物的研究
Kiarash Saleki,Moein Shirzad,Sheyda Mohammadkhani et al.
Kiarash Saleki et al.
Background: Monocyte chemoattractant protein 1 (MCP1/CCL2) and matrix metalloproteinase (MMP9) in COVID-19 Patients are key immune elements that may be involved in COVID-19-induced cytokine storm. ...
A colorimetric amplification-based method for identification of Moraxella catarrhalis, a human respiratory tract pathogen [0.03%]
一种基于色彩放大原理的莫拉克菌鉴定方法
Kiana Gholizad Monavari,Hamidreza Mollasalehi
Kiana Gholizad Monavari
Moraxella catarrhalis is a significant pathogen associated with both upper and lower respiratory tract infections. This study aims to identify M. catarrhalis using the ompCD gene, which encodes a major outer membrane protein. Spectrophotome...