Comprehensive analysis of the deleterious nonsynonymous, non-coding SNPs and cancer variants of human aldo-keto reductase type 1 (AKR1C1) protein and their probable association with disease risk and progression: a computational study
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Aldo-keto reductase family 1 member C1 (AKR1C1) is a key enzyme involved in steroid hormone and xenobiotic metabolism and has been implicated in hormone-dependent cancers, chemoresistance, and inflammatory disorders. Genetic variation in AKR1C1 may influence e... ...
