Triggering charge redistribution-induced oxygen spillover mechanism in VO x-supported IrSn alloy toward industrial water electrolysis [0.03%]
VOx负载IrSn合金催化剂诱发的电荷重新分布诱导的氧溢流机制用于工业水电解反应
Zijie Lin,Jiashun Liang,Hao Shi et al.
Zijie Lin et al.
Developing advanced iridium (Ir)-based oxygen evolution reaction (OER) catalysts is critical for proton exchange membrane water electrolyzers (PEMWEs). Unfortunately, conventional adsorbate evolution mechanism (AEM) and lattice oxygen mecha...
A biodegradable piezoelectric vertebral implant for programmable electro-neuromodulation in spinal cord injury [0.03%]
一种可生物降解的压电椎间植入物用于脊髓损伤的编程式电神经调节
Penghao Liu,Xinyu Wang,Yanchun Liu et al.
Penghao Liu et al.
Spinal cord stimulation has emerged as a promising therapeutic strategy for spinal cord injury (SCI), yet conventional electronic implants remain limited by surgical risk and long-term safety concerns. We introduce a biodegradable piezoelec...
Dopamine depletion in Parkinson's increases directed but not random exploration [0.03%]
多巴胺缺乏增加帕金森病患者定向但不影响随机探索行为
Björn Meder,Martha Sterf,Charley M Wu et al.
Björn Meder et al.
We investigated how patients with Parkinson's disease (PD) manage the explore-exploit trade-off in a structured reward-learning task. Patients were tested either on (n = 34) or off (n = 34) dopaminergic medication (levodopa), with age-match...
A metabolite morphogen coordinates multicellular development in Bacillus subtilis [0.03%]
芽孢杆菌亚种的代谢产物形态发生素协调多细胞发育
Taylor B Updegrove,Vani Pande,Fukang She et al.
Taylor B Updegrove et al.
The transition from unicellular to multicellular growth requires diversification of cellular functions within genetically identical populations. In Bacillus subtilis, biofilm formation is historically viewed as a developmental precursor to ...
A clinical and experimental investigation of liraglutide effects on the brain-kidney axis [0.03%]
利拉鲁肽对脑-肾轴影响的临床和实验研究
Michael P Greenwood,Mohammed I Alotaibi,Soledad Bárez-López et al.
Michael P Greenwood et al.
Glucagon-like peptide-1 receptor agonists elicit diuresis and natriuresis in humans and rodents. However, little is known about their interactions with the bodies hormonal systems that control fluid homeostasis. We performed a single center...
Aaron Clauset,Barbara F Walter,Lars-Erik Cederman et al.
Aaron Clauset et al.
Although very large wars remain an enduring threat in global politics, we lack a clear understanding of how some wars become large and costly, while most do not. There are three possibilities: Large conflicts begin with intense fighting, ac...
Anisotropic variable negative-Poisson-ratio metamaterials for tunable multispectral camouflage and electromagnetic energy harvesting [0.03%]
各向异性可调多光谱仿生迷彩及电磁能量采集变结构性材料
Xiaofen Yang,Kaixia Yang,Meiwan Ying et al.
Xiaofen Yang et al.
Adaptive electromagnetic compatibility, camouflage, and energy conversion raises challenge in the swiftly responsive modulation. Herein, we designed pixelated negative-Poisson-ratio metamaterials that enable fast control over structural ani...
Dasatinib reversibly disrupts T cell motility and activation in lymph nodes [0.03%]
Dasatinib可逆地破坏淋巴结T细胞的运动和活化
Daniela Claudino Carvoeiro,Ana Marcos-Jiménez,Ilya Tsukalov et al.
Daniela Claudino Carvoeiro et al.
The tyrosine kinase inhibitor dasatinib is prescribed as a first-line treatment for Philadelphia chromosome-positive leukemias and is increasingly used in other clinical settings. While dasatinib is effective and generally well tolerated, p...
Intermediate stages in the origin of metabolism at a phosphorylating hydrothermal vent [0.03%]
含磷酸化热液喷口代谢起源的中间阶段
Natalia Mrnjavac,Nadja K Hoffmann,Manon L Schlikker et al.
Natalia Mrnjavac et al.
The origin of life required the emergence of metabolism, an autocatalytic network of enzymatic reactions that synthesize amino acids, nucleotides, and cofactors. At the origin of metabolism, there were no enzymes-how did it start? Empirical...
A temporal differentiation program after birth delineates γδ T cell immunity [0.03%]
出生后的时序分化程序确定了γδ T细胞免疫功能
Maria V Baglioni,Marcelo G F Fares da Silva,Andrea Sonnenholzner et al.
Maria V Baglioni et al.
Type 1 and type 3 γδ T cells develop in the embryonic thymus, yet it is not known whether they continue to differentiate after birth in tissues. Here, we show that in the first week of life, intestinal γδ T cells up-regulated many T cel...