Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake [0.03%]
凋亡小体促进骨再生的机制研究
Yawen Cheng,Yuan Zhu,Yaoshan Liu et al.
Yawen Cheng et al.
Accumulating evidence has demonstrated that apoptotic vesicles (apoVs) derived from mesenchymal stem cells (MSCs; MSC-apoVs) are vital for bone regeneration, and possess superior capabilities compared to MSCs and other extracellular vesicle...
Expert consensus on pediatric orthodontic therapies of malocclusions in children [0.03%]
儿童错𬌗畸形早期矫治专家共识
Chenchen Zhou,Peipei Duan,Hong He et al.
Chenchen Zhou et al.
Malocclusion, identified by the World Health Organization (WHO) as one of three major oral diseases, profoundly impacts the dental-maxillofacial functions, facial esthetics, and long-term development of ~260 million children in China. Beyon...
Tetrahedral framework nucleic acids/hyaluronic acid-methacrylic anhydride hybrid hydrogel with antimicrobial and anti-inflammatory properties for infected wound healing [0.03%]
一种用于感染伤口修复的四面体网格核酸/透明质酸-甲酸酐混合交联水凝胶及其抗菌抗炎性能
Cai Qi,Qiang Sun,Dexuan Xiao et al.
Cai Qi et al.
Bacterial resistance and excessive inflammation are common issues that hinder wound healing. Antimicrobial peptides (AMPs) offer a promising and versatile antibacterial option compared to traditional antibiotics, with additional anti-inflam...
Single cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification [0.03%]
单细胞分析揭示头颈鳞癌B细胞为主的免疫亚型并进行改善预后和治疗的分层
Kang Li,Caihua Zhang,Ruoxing Zhou et al.
Kang Li et al.
Head and neck squamous cell carcinoma (HNSCC) is characterized by high recurrence or distant metastases rate and the prognosis is challenging. There is mounting evidence that tumor-infiltrating B cells (TIL-Bs) have a crucial, synergistic r...
The evolution of robotics: research and application progress of dental implant robotic systems [0.03%]
口腔种植机器人系统研究及应用进展
Chen Liu,Yuchen Liu,Rui Xie et al.
Chen Liu et al.
The use of robots to augment human capabilities and assist in work has long been an aspiration. Robotics has been developing since the 1960s when the first industrial robot was introduced. As technology has advanced, robotic-assisted surger...
FUT8-mediated aberrant N-glycosylation of SEMA7A promotes head and neck squamous cell carcinoma progression [0.03%]
FUT8介导的SEMA7A异常岩藻糖基化促进口腔鳞癌进展
Zhonglong Liu,Xiaoyan Meng,Yuxin Zhang et al.
Zhonglong Liu et al.
SEMA7A belongs to the Semaphorin family and is involved in the oncogenesis and tumor progression. Aberrant glycosylation has been intricately linked with immune escape and tumor growth. SEMA7A is a highly glycosylated protein with five glyc...
Periodontitis exacerbates pulmonary hypertension by promoting IFNγ+ T cell infiltration in mice [0.03%]
牙周炎通过促进小鼠中IFNγ+t细胞浸润加剧肺动脉高压
Xiaoqian Meng,Linjuan Du,Shuo Xu et al.
Xiaoqian Meng et al.
Uncovering the risk factors of pulmonary hypertension and its mechanisms is crucial for the prevention and treatment of the disease. In the current study, we showed that experimental periodontitis, which was established by ligation of molar...
A Wnt10a-Notch signaling axis controls Hertwig's epithelial root sheath cell behaviors during root furcation patterning [0.03%]
Wnt10a-Notch信号轴控制Hertwig上皮根鞘细胞在根分叉模式中的行为
Kai Sun,Miao Yu,Jiayu Wang et al.
Kai Sun et al.
Human with bi-allelic WNT10A mutations and epithelial Wnt10a knockout mice present enlarged pulp chamber and apical displacement of the root furcation of multi-rooted teeth, known as taurodontism; thus, indicating the critical role of Wnt10...
Promising dawn in tumor microenvironment therapy: engineering oral bacteria [0.03%]
肿瘤微环境治疗中令人鼓舞的进展：口腔细菌工程
Zifei Wang,Wansu Sun,Ruixue Hua et al.
Zifei Wang et al.
Despite decades of research, cancer continues to be a major global health concern. The human mouth appears to be a multiplicity of local environments communicating with other organs and causing diseases via microbes. Nowadays, the role of o...
Expert consensus on irrigation and intracanal medication in root canal therapy [0.03%]
根管治疗中冲洗及根管内给药的专家共识
Xiaoying Zou,Xin Zheng,Yuhong Liang et al.
Xiaoying Zou et al.
Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the apical region has yet to be solved...