The research progress on periodontitis by the National Natural Science Foundation of China [0.03%]
我国国家自然科学基金资助的牙周病学研究进展
Liang Xie,Qian Chen,Hao Xu et al.
Liang Xie et al.
Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in Chi...
Physiologically relevant coculture model for oral microbial-host interactions [0.03%]
口腔微生物-宿主互作的生理相关共培养模型
Zeyang Pang,Nicole M Cady,Lujia Cen et al.
Zeyang Pang et al.
Understanding microbial-host interactions in the oral cavity is essential for elucidating oral disease pathogenesis and its systemic implications. In vitro bacteria-host cell coculture models have enabled fundamental studies to characterize...
Author Correction: Organoids in the oral and maxillofacial region: present and future [0.03%]
作者更正：口腔和颌面部类器官的现状与未来
Yufei Wu,Xiang Li,Hanzhe Liu et al.
Yufei Wu et al.
Published Erratum
International journal of oral science. 2025 May 27;17(1):43. DOI:10.1038/s41368-025-00377-5 2025
Osteomodulin modulates the inflammatory responses via the interleukin-1 receptor 1/nuclear factor-κB signaling pathway in dental pulpitis [0.03%]
骨模素通过白细胞介素-1受体1/核因子-κB信号途径调节牙髓炎的炎症反应
Yueyi Yang,Xuchen Hu,Meiling Jing et al.
Yueyi Yang et al.
Pulpitis is a common infective oral disease in clinical situations. The regulatory mechanisms of immune defense in pulpitis are still being investigated. Osteomodulin (OMD) is a small leucine-rich proteoglycan family member distributed in b...
Single-cell and spatial transcriptomics reveals an anti-tumor neutrophil subgroup in microwave thermochemotherapy-treated lip cancer [0.03%]
单细胞和空间转录组揭示微波热化疗治疗唇癌中具有抗肿瘤作用的中性粒细胞亚群
Bingjun Chen,Huayang Fan,Xin Pang et al.
Bingjun Chen et al.
Microwave thermochemotherapy (MTC) has been applied to treat lip squamous cell carcinoma (LSCC), but a deeper understanding of its therapeutic mechanisms and molecular biology is needed. To address this, we used single-cell transcriptomics ...
Profiling and functional characterization of long noncoding RNAs during human tooth development [0.03%]
人牙发育过程中长链非编码RNA的特征分析及功能表征
Xiuge Gu,Wei Wei,Chuan Wu et al.
Xiuge Gu et al.
The regulatory processes in developmental biology research are significantly influenced by long non-coding RNAs (lncRNAs). However, the dynamics of lncRNA expression during human tooth development remain poorly understood. In this research,...
Expansion of functional human salivary acinar cell spheroids with reversible thermo-ionically crosslinked 3D hydrogels [0.03%]
具有可逆热离子交联的三维水凝胶的人涎腺腺泡细胞球体的扩增
Jose G Munguia-Lopez,Sangeeth Pillai,Yuli Zhang et al.
Jose G Munguia-Lopez et al.
Xerostomia (dry mouth) is frequently experienced by patients treated with radiotherapy for head and neck cancers or with Sjögren's syndrome, with no permanent cure existing for this debilitating condition. To this end, in vitro platforms a...
Community dynamics during de novo colonization of the nascent peri-implant sulcus [0.03%]
种植体表面唾液接触区微生物群的从头定植及早期变化规律研究
Tamires Pereira Dutra,Nicolas Robitaille,Khaled Altabtbaei et al.
Tamires Pereira Dutra et al.
Dental implants have restored masticatory function to over 100 000 000 individuals, yet almost 1 000 000 implants fail each year due to peri-implantitis, a disease triggered by peri-implant microbial dysbiosis. Our ability to prevent and tr...
Mandible-derived extracellular vesicles regulate early tooth development in miniature swine via targeting KDM2B [0.03%]
下颌来源的细胞外囊泡通过靶向KDM2B调控 miniature pig早期牙发育
Ye Li,Meng Sun,Yi Ding et al.
Ye Li et al.
Tissue interactions play a crucial role in tooth development. Notably, extracellular vesicle-mediated interactions between the mandible and tooth germ are considered essential. Here, we revealed that mandible extracellular vesicles could mo...
Single-cell sequencing systematically analyzed the mechanism of Emdogain on the restoration of delayed replantation periodontal membrane [0.03%]
单细胞测序技术系统分析Emdogain修复延期再植牙周膜的作用机制
Yanyi Liu,Yuhao Peng,Lanhui Chen et al.
Yanyi Liu et al.
The repair of the periodontal membrane is essential for the successful management of periodontal disease and dental trauma. Emdogain® (EMD) is widely used in periodontal therapy due to its ability to promote repair. Despite substantial res...