Porphyromonas gingivalis potentiates stem-like properties of oral squamous cell carcinoma by modulating SCD1-dependent lipid synthesis via NOD1/KLF5 axis [0.03%]
口腔鳞状细胞癌中Porphyromonas gingivalis通过NOD1/KLF5轴调节SCD1依赖的脂质合成增强干细胞样特性
Wenli Zang,Fengxue Geng,Junchao Liu et al.
Wenli Zang et al.
Cancer stem cells (CSCs) are widely acknowledged as primary mediators to the initiation and progression of tumors. The association between microbial infection and cancer stemness has garnered considerable scholarly interest in recent years....
Circadian disruption by simulated shift work aggravates periodontitis via orchestrating BMAL1 and GSDMD-mediated pyroptosis [0.03%]
模拟轮班工作引起的昼夜节律紊乱通过调节BMAL1和GSDMD介导的焦亡加重牙周炎
Yazheng Wang,Rui Li,Qingyuan Ye et al.
Yazheng Wang et al.
Approximately 20% to 30% of the global workforce is engaged in shift work. As a significant cause of circadian disruption, shift work is closely associated with an increased risk for periodontitis. Nevertheless, how shift work-related circa...
Emerging roles of extracellular vesicles in oral and maxillofacial areas [0.03%]
口腔和颌面部区域的细胞外囊泡的作用机制及其新兴作用
Qianting Wang,Jiayu Sun,Haci Jiang et al.
Qianting Wang et al.
The oral and maxillofacial region is a highly complex area composed of multiple tissue types and bears various critical functions of the human body. Diseases in this region pose significant diagnostic and management challenges; therefore, e...
Jianfei Tang,Junjie Liu,Zekun Zhou et al.
Jianfei Tang et al.
Oral submucous fibrosis (OSF), characterized by excessive deposition of extracellular matrix (ECM) that causes oral mucosal tissue sclerosis, and even cancer transformation, is a chronic, progressive fibrosis disease. However, despite some ...
Jie Pan,Yun Lu,Anqi Liu et al.
Jie Pan et al.
Protrusive facial deformities, characterized by the forward displacement of the teeth and/or jaws beyond the normal range, affect a considerable portion of the population. The manifestations and morphological mechanisms of protrusive facial...
Strontium-Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment [0.03%]
增强滑膜间充质干细胞源外泌体中miRNA选择性负载治疗颞下颌关节骨关节炎
Wenxiu Yuan,Jiaqi Liu,Zhenzhen Zhang et al.
Wenxiu Yuan et al.
The ambiguity of etiology makes temporomandibular joint osteoarthritis (TMJOA) "difficult-to-treat". Emerging evidence underscores the therapeutic promise of exosomes in osteoarthritis management. Nonetheless, challenges such as low yields ...
GenAI synthesis of histopathological images from Raman imaging for intraoperative tongue squamous cell carcinoma assessment [0.03%]
基于拉曼成像的基因AI合成组织病理图像用于术中评估舌鳞状细胞癌
Bing Yan,Zhining Wen,Lili Xue et al.
Bing Yan et al.
The presence of a positive deep surgical margin in tongue squamous cell carcinoma (TSCC) significantly elevates the risk of local recurrence. Therefore, a prompt and precise intraoperative assessment of margin status is imperative to ensure...
The impact of aging on neutrophil functions and the contribution to periodontitis [0.03%]
衰老对中性粒细胞功能的影响及其在牙周炎发生中的作用
Zi Wang,Anish Saxena,Wenbo Yan et al.
Zi Wang et al.
The increasing aging population and aging-associated diseases have become a global issue for decades. People over 65 show an increased prevalence and greater severity of periodontitis, which poses threats to overall health. Studies have dem...
Tongue squamous cell carcinoma-targeting Au-HN-1 nanosystem for CT imaging and photothermal therapy [0.03%]
舌黏膜鳞癌的CT成像及光热治疗的Au-HN-1纳米系统肿瘤分子影像及诊疗新技术研究国际研讨会会议论文集
Ming Hao,Xingchen Li,Xinxin Zhang et al.
Ming Hao et al.
Tongue squamous cell carcinoma (TSCC) is a prevalent malignancy that afflicts the head and neck area and presents a high incidence of metastasis and invasion. Accurate diagnosis and effective treatment are essential for enhancing the qualit...
Adhesive and injectable hydrogel microspheres for NRF2-mediated periodontal bone regeneration [0.03%]
基于NRF2的牙周骨再生可粘附和注射型水凝胶微球的研究
Yu Wang,Shanshan Jin,Yaru Guo et al.
Yu Wang et al.
Regenerating periodontal bone defect surrounding periodontal tissue is crucial for orthodontic or dental implant treatment. The declined osteogenic ability of periodontal ligament stem cells (PDLSCs) induced by inflammation stimulus contrib...