Selenoprotein H mediates low selenium-related cognitive decline through impaired oligodendrocyte myelination with disrupted hippocampal lipid metabolism in female mice [0.03%]
硒蛋白H通过干扰小胶质细胞少突胶质细胞髓鞘化和海马脂质代谢紊乱介导低硒致雌鼠认知障碍
Qingqing Lv,Aolin Yang,Ziyu Han et al.
Qingqing Lv et al.
Low selenium levels are closely associated with reduced cognitive performance and lipid dysregulation, yet the mechanism of action remains unclear. The physiological function of selenium is primarily mediated by selenoproteins. Selenoprotei...
Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory [0.03%]
富含高酚类可可的饮食增强健康成人鼠海马脑源性神经营养因子表达和神经发生及其对记忆的细微影响
Sonia Melgar-Locatelli,M Carmen Mañas-Padilla,Adriana Castro-Zavala et al.
Sonia Melgar-Locatelli et al.
Cocoa is widely known for its health benefits, but its neurocognitive impact remains underexplored. This preclinical study aimed to investigate the effects of cocoa and cocoa polyphenols on hippocampal neuroplasticity, cognitive function an...
Mulberry polyphenols restored both small and large intestinal microflora in db/ db mice, potentially alleviating type 2 diabetes [0.03%]
桑葚多酚可同时改善db/db小鼠的小肠和大肠菌群失调，从而缓解2型糖尿病
Fuhua Li,Jian Ming
Fuhua Li
Polyphenols in mulberry fruit have potential anti-diabetic effects by targeting the gut microbiota. This study investigated how mulberry polyphenols (MPs) influence the microbiota of the small and large intestines and their effects on type ...
Associations of dietary patterns with risk of gastrointestinal disorders: a prospective cohort study [0.03%]
饮食模式与胃肠疾病发病风险的关联：一项前瞻性队列研究
Weiyi Chen,Yingying Zhao,Haojie Lu et al.
Weiyi Chen et al.
Gastrointestinal (GI) disorders are highly prevalent and severely diminish life quality. It is yet unknown which dietary pattern is optimal for the prevention of GI disorders. Among 141 450 participants from UK Biobank with a median follow-...
Ovomucin and its hydrolysates differentially influenced colitis severity in Citrobacter rodentium-infected mice [0.03%]
卵粘蛋白及其水解产物通过不同机制影响鼠伤寒沙雷菌感染小鼠结肠炎的严重程度
Xiaoyu Bao,Tingting Ju,Stephanie Tollenaar et al.
Xiaoyu Bao et al.
Egg white protein ovomucin and its hydrolysates were previously reported to exhibit anti-inflammatory and anti-adhesive activities. However, their potential to regulate pathogen colonization and disease severity has not been fully character...
Urinary alkylresorcinol metabolites, biomarkers of whole grain wheat and rye intake, are beneficially associated with liver fat and other fat measures [0.03%]
尿烷基树脂酚代谢物，整个小麦和黑麦摄入的生物标志物与其他脂肪测量值有益联系在一起肝脏脂肪
Zisuo Sun,Yaling Shao,Xiaoyu Zhang et al.
Zisuo Sun et al.
Aims: Epidemiological studies that use dietary biomarkers to investigate the association between whole grain intake and the risk of obesity are sparse. We assessed the association between urinary alkylresorcinol metabolites including 3-(3,5...
A high-fat diet induced depression-like phenotype via hypocretin-HCRTR1 mediated inflammation activation [0.03%]
高脂饮食通过下丘脑分泌素-HCRTR1介导的炎症激活诱导类似抑郁表型
Jingyi Dong,Jinghui Zhang,Shangping Cheng et al.
Jingyi Dong et al.
Background: A high-fat diet (HFD) is generally associated with an increased risk of mental disorders that constitute a sizeable worldwide health. A HFD results in the gut microbiota-brain axis being altered and linked to mental disorders. H...
Tea, coffee, and caffeine intake and risk of dementia and Alzheimer's disease: a systematic review and meta-analysis of cohort studies [0.03%]
茶、咖啡和咖啡因摄入与痴呆症和阿尔茨海默病风险的关系：队列研究的系统评价和荟萃分析
Fengjuan Li,Xiaoning Liu,Bin Jiang et al.
Fengjuan Li et al.
Background: Limited and conflicting evidence exists for the associations between tea, coffee, and caffeine intake and risk of dementia and Alzheimer's disease (AD). This meta-analysis aimed to elucidate these associations and quantify poten...
Meta-Analysis
Food & function. 2024 Aug 12;15(16):8330-8344. DOI:10.1039/d4fo01750a 2024
In vivo absorption and excretion in rats and in vitro digestion and fermentation by the human intestinal microbiota of 2- O-β-D-glucopyranosyl-L-ascorbic acid from the fruits of Lycium barbarum L [0.03%]
2- O- β-D-葡萄吡喃糖基-L-抗坏血酸的体内吸收和排泄以及体外消化代谢产物的发酵研究：枸杞果中的2- O- β-D-葡萄吡喃糖抗坏血酸的研究
Wei Dong,Yujia Peng,Weiqi Xu et al.
Wei Dong et al.
2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG) from Lycium barbarum fruits has diverse bioactivities, yet its absorption and digestion are poorly understood. Therefore, the in vivo absorption of AA-2βG in rats was investigated in the pr...
Nutritional, antioxidant and biological activity characterization of orange peel flour to produce nutraceutical gluten-free muffins [0.03%]
橙皮粉特征化以生产具有营养、抗氧化和生物活性的无谷蛋白马芬面包的研究
Giusy Rita Caponio,Alessandro Annunziato,Mirco Vacca et al.
Giusy Rita Caponio et al.
Celiac disease - a prevalent food intolerance - requires strict adherence to a lifelong gluten-free (GF) diet as the only effective treatment. However, GF products often lack soluble fibre and have a high glycaemic index. Consequently, ther...