RRM2 attenuates renal tubular ferroptosis in diabetic kidney disease vi a the PI3K/Akt/Nrf2 pathway: Strengths, limitations, and future research directions [0.03%]
RRM2通过PI3K/Akt/Nrf2途径减弱糖尿病肾病中的肾小管铁死亡:优势、局限性及未来研究方向
Ying-Chun Liu,Jing Xiao,Lin Chen
Ying-Chun Liu
Diabetic kidney disease (DKD) has become the primary cause of end-stage renal disease. However, its pathological mechanism remains incompletely understood. Ribonucleotide reductase M2 (RRM2) is a small subunit of ribonucleotide reductases, ...
Safety and efficacy of sodium-glucose cotransporter-2 inhibitors in adults with type 2 diabetes fasting during Ramadan: A meta-analysis [0.03%]
钠葡萄糖协同转运蛋白2抑制剂在斋月封斋的2型糖尿病成人患者中的安全性和有效性:一项系统综述和.meta.分析
Abul Bashar Mohammad Kamrul-Hasan,Shehla Shaikh,Hamid Ashraf et al.
Abul Bashar Mohammad Kamrul-Hasan et al.
Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are widely used in managing type 2 diabetes (T2D). A significant number of these patients choose to observe religious fasting during Ramadan. Although existin...
Metabolic dysfunction-associated steatotic liver disease and type 2 diabetes: Pathophysiology, diagnosis, and emerging therapeutic strategies [0.03%]
与2型糖尿病相关的代谢紊乱联发脂肪性肝病:病理生理、诊断和潜在的治疗策略
Mithil Gowda Suresh,Safia Mohamed,Harinivaas S Geetha et al.
Mithil Gowda Suresh et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD), the updated terminology for fatty liver disease linked to metabolic dysfunction, is highly prevalent among individuals with type 2 diabetes mellitus (T2DM). MASLD affects a m...
Diabetes prolongs hospitalization and increases infection, cerebral edema, and neurological complications in meningioma patients: A retrospective study [0.03%]
糖尿病延长脑膜瘤患者的住院时间并增加感染、脑水肿和神经并发症的发生:一项回顾性研究
Yu-Fu Zhang,Wei Ma,Long Chen et al.
Yu-Fu Zhang et al.
Background: Diabetes is linked to extended hospitalization and a heightened risk of complications in multiple surgical settings. However, its precise influence on outcomes in patients undergoing meningioma resection is st...
Renal and metabolic effects of semaglutide plus canagliflozin vs canagliflozin alone in type 2 diabetic nephropathy [0.03%]
塞马鲁肽联合卡格列净与单纯使用卡格列净对2型糖尿病肾病的肾脏及代谢效应的影响
Yan Miao,Pan He,Dan-Yu Wang et al.
Yan Miao et al.
Background: Diabetic nephropathy (DN) is a major microvascular complication of type 2 diabetes and a leading cause of end-stage renal disease. Both canagliflozin and semaglutide are recommended for diabetic nephropathy, y...
Enhancing dental implant outcomes in type 2 diabetes: Addressing inflammation and risk factors [0.03%]
2型糖尿病患者的牙种植体感染及危险因素的干预措施改善种植体预后
Li-Feng Xiao,Yi-Xuan Xing,Nian-Zhe Sun
Li-Feng Xiao
This article contextualizes the recent study by Li et al within the broader challenge of achieving dental implant success in patients with type 2 diabetes mellitus (T2DM). The original article by Li et al provides a thorough retrospective a...
COVID-19 outbreak on the seasonality and incidence of pediatric type 1 diabetes mellitus [0.03%]
新冠肺炎疫情对儿童1型糖尿病季节性和发病的影响研究
Andrea Scaramuzza,Claudio Cavalli
Andrea Scaramuzza
To respond to the recent study by Carmon et al on type 1 diabetes (T1DM) incidence/seasonality pre-coronavirus disease 2019 and peri-coronavirus disease 2019, we highlighted convergent findings from the Lombardy pediatric T1DM data (2017-20...
Using the triglyceride-glucose index and derived indexes to forecast progression from pre-diabetes to diabetes: A 3-year follow-up study [0.03%]
使用三酰甘油-葡萄糖指数及其衍生指标预测糖尿病前期进展为糖尿病:一项为期三年的随访研究
Bing Wang,Ming-Chuan Liu,Xu-Han Liu et al.
Bing Wang et al.
Background: Pre-diabetes is a transitional metabolic stage between health and diabetes, serving as a critical warning signal for disease progression. Early intervention targeting risk factors in prediabetic individuals pr...
Electroacupuncture protects gastric Cajal cells by reducing macrophage pyroptosis in diabetic gastroparesis [0.03%]
电针通过减少巨噬细胞焦亡保护糖尿病胃轻瘫卡哈尔细胞
Ming-Wei Fan,Jin-Lan Tian,Shu-Hui Zhang et al.
Ming-Wei Fan et al.
Background: This study elucidates the mechanisms through which electroacupuncture (EA) at Zusanli acupoint, applied at different frequencies, alleviates diabetic gastroparesis (DGP). The modulation of the cyclic GMP-AMP s...
Formononetin inhibits p53 signaling pathway activation to delay cellular senescence and ameliorates diabetic kidney disease [0.03%]
黄豆苷元通过抑制p53信号通路延缓细胞衰老进而改善糖尿病肾病
Yue Ji,Rui-Xin Liu,Pei-Yue He et al.
Yue Ji et al.
Background: Diabetic kidney disease (DKD) continues to pose a substantial public health challenge, in which cellular senescence is recognized as a pivotal driver of disease progression. While formononetin (FN) has been do...