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RRM2 attenuates renal tubular ferroptosis in diabetic kidney disease vi a the PI3K/Akt/Nrf2 pathway: Strengths, limitations, and future research directions

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Diabetic kidney disease (DKD) has become the primary cause of end-stage renal disease. However, its pathological mechanism remains incompletely understood. Ribonucleotide reductase M2 (RRM2) is a small subunit of ribonucleotide reductases, which is involved in... ...