Curcumol targets the FTO/MAFG-AS1 axis to alleviate diabetic retinopathy via epigenetic remodeling and nanodelivery-based microenvironment modulation [0.03%]
姜黄素衍生物Curcumol通过表观遗传重编程和基于纳米递送的微环境调控靶向FTO/MAFG-AS1轴缓解糖尿病视网膜病变
Cheng Luo,Zhi-Gang Zheng,Mei-Qi Zeng et al.
Cheng Luo et al.
Diabetic retinopathy (DR) is a major microvascular complication of diabetes, with its pathogenesis involving metabolic memory, epigenetic dysregulation, and multi-cellular microenvironmental disorders. This study systematically investigates...
Long-term risk of diabetes following hypertensive disorders of pregnancy: A retrospective cohort study [0.03%]
妊娠期高血压疾病的长期糖尿病风险:一项回顾性队列研究
Yu-Hsiang Shih,Chiao-Yu Yang,Chia-Chi Lung
Yu-Hsiang Shih
Background: The impact of varying degrees of pregnancy-induced hypertension (PIH) on the risk of developing diabetes later in life is currently unknown. A...
Beyond glycemic control: Roles for sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor agonists in diabetic kidney disease [0.03%]
超越血糖控制:钠葡萄糖共转运体2抑制剂和胰高血糖素样肽1受体激动剂在糖尿病肾脏疾病中的作用
Gabriel Lc Santos,Clara Fsm Dos Santos,Gabriel R Rocha et al.
Gabriel Lc Santos et al.
The global prevalence of diabetes has surged in recent years, with diabetic kidney disease (DKD) emerging as a major complication. Traditional therapies have had limited success in slowing progression to end-stage kidney disease. However, n...
Trends and predictors of diabetes mellitus after living kidney transplantation: A retrospective study [0.03%]
糖尿病肾移植患者的糖尿病患病趋势及预测因素:回顾性研究
Amil Huseynov,Sevim Nuran Kuşlu Çicek
Amil Huseynov
Background: Post-transplant diabetes mellitus (PTDM) is a common metabolic adverse event following kidney transplantation, negatively impacting graft function and patient outcomes. ...
Association between anemia and the risk of diabetic foot ulcer: A meta-analysis [0.03%]
贫血与糖尿病足溃疡风险的相关性:一项荟萃分析
Shi-Shuai Lin,Cun-Ren Chen,Wei-Cheng Xu et al.
Shi-Shuai Lin et al.
Background: Diabetic foot ulcers (DFUs) are a major complication of diabetes mellitus, and anemia is commonly observed in diabetic patients. However, the relationship between anemia and the risk of developing DFUs remains...
Ras homolog enriched in brain 1 regulates β cell mass and β cell function via mTORC1/AMPK/Notch1 pathways [0.03%]
Ras脑富集蛋白1通过mTORC1/AMPK/诺特定点1途径调节β细胞质量和β细胞功能
Yan Yang,Wan-Juan Song,Jing-Jing Zhang
Yan Yang
Background: The identification of key regulators of β cell mass and function is crucial in developing effective therapeutic interventions for diabetes. Ras homolog enriched in brain 1 (Rheb1), an upstream binding protein...
Is there a role for platelet indices in predicting poor glucoregulation in type 2 diabetes mellitus? [0.03%]
血小板指标预测2型糖尿病患者糖代谢紊乱的作用探讨
Gabriel Araújo Medeiros,Jan B Felinto de Santana,Lenita Zajdenverg et al.
Gabriel Araújo Medeiros et al.
In this editorial, we discuss the recent article by Regassa et al, published in the World Journal of Diabetes, which highlights the potential role of platelet indices (PI) in predicting poor glucoregulation in patients with type 2 diabetes ...
Iron dysregulation, ferroptosis, and oxidative stress in diabetic osteoporosis: Mechanisms, bone metabolism disruption, and therapeutic strategies [0.03%]
糖尿病性骨质疏松症中的铁失调、铁依赖性细胞死亡及氧化应激:机制、骨代谢紊乱与治疗策略
Yao-Bin Wang,Zhi-Peng Li,Peng Wang et al.
Yao-Bin Wang et al.
Diabetic osteoporosis (DOP) is a common complication in diabetes, driven by hyperglycemia-induced metabolic disturbances, chronic inflammation, and oxidative stress. This review describes the critical role of iron metabolism dysregulation i...
Longitudinal effects of Johnson & Johnson COVID-19 vaccination on metabolic biomarkers in type 2 diabetes mellitus in Ethiopia [0.03%]
强生公司COVID-19疫苗对埃塞俄比亚2型糖尿病患者代谢生物标志物的纵向影响
Chala Kenenisa Edae,Abdisa Tufa Bedada,Maria Degef Teklemariam et al.
Chala Kenenisa Edae et al.
Background: The coronavirus disease 2019 (COVID-19) pandemic has disproportionately impacted individuals with type 2 diabetes mellitus (T2DM), increasing their risk of severe illness and mortality. Vaccination has been a ...
Associations of nontraditional lipoprotein ratios with future cardiovascular events in patients with type 2 diabetes mellitus [0.03%]
非传统脂蛋白比值与2型糖尿病患者未来心血管事件的关系
Si-Min Deng,Xin-Qun Hu,Xiang-Yu Zhang
Si-Min Deng
Background: Patients with type 2 diabetes mellitus (T2DM) face a heightened risk of future cardiovascular events. It is therefore important to stratify these patients according to their future cardiovascular event risk to...