Extending wave propagation along muscle fibers originates from early local contraction at the end-plate region [0.03%]
肌纤维起始处终板区域的早期局部收缩引发波沿肌肉纤维传播
Tomonori Hayashi,Naoya Nakahara,Shigeru Morimoto et al.
Tomonori Hayashi et al.
We investigated the propagation of extending waves along twitching muscle fibers triggered by the internal shortening of early local contraction in the end-plate region. Bullfrog sartorius muscles were minimally stimulated, and the displace...
Selective serotonin reuptake inhibitors (SSRIs) suppress Na+- dependent Mg2+ efflux in rat ventricular myocytes [0.03%]
选择性5-羟色胺再摄取抑制剂(SSRI)抑制大鼠心室肌细胞Na+-依赖性Mg2+外排
Michiko Tashiro,Masato Konishi,Hana Inoue et al.
Michiko Tashiro et al.
Na+/Mg2+ exchange transport, the Na+ gradient-driven Mg2+ extrusion system, plays a key role in cellular Mg2+ homeostasis. To date, the molecular entity and selective inhibitors of Na+/Mg2+ exchanger have not been fully explored. Intracellu...
Influence of endurance versus resistance exercise training on central and peripheral chemoreflexes in young healthy individuals [0.03%]
有氧运动与抗阻训练对健康年轻受试者中枢和外周化学感受器的影响
Thalia Babbage,Ana L C Sayegh,Jui-Lin Fan et al.
Thalia Babbage et al.
Heightened central and peripheral chemoreflex sensitivity are associated with poor outcomes, but therapeutic approaches to target them are lacking. Endurance and resistance exercise training improve a multitude of physiological outcomes, bu...
Acute transcutaneous CO2 exposure: A feasibility study for the future investigation of CO2-specific exercise adaptations [0.03%]
急性二氧化碳暴露的研究：未来探究二氧化碳特异性运动适应性的可行性研究
Kyle M A Thompson,Avery Bendell,Jamie F Burr
Kyle M A Thompson
Blood flow restricted (BFR) exercise induces musculoskeletal adaptations at reduced exercise loads. The role of hypercapnia during BFR remains unclear, due to difficulties in isolating this factor in vivo. We evaluated a hypercapnic model d...
Makoto Tominaga
Makoto Tominaga
Heart rate changes related to risky selections and outcomes in rat gambling tasks [0.03%]
大鼠赌博任务中风险选择和结果相关的心率变化
Fumiya Fukushima,Atsushi Tamura,Nahoko Kuga et al.
Fumiya Fukushima et al.
Risk-taking behavior is crucial to increase potential outcomes and alter arousal states in the brain and body represented by heart rates. In this study, we monitored changes in heart rate as rats performed a 50:50 gambling task in which the...
Resistance training-induced dihydrotestosterone is blunted in aging rat skeletal muscle [0.03%]
抗阻力训练诱导的双氢睾酮在衰老大鼠骨骼肌中的钝化作用
Yung-Li Hung,Akihito Ishigami,Shuichi Machida
Yung-Li Hung
This study aimed to investigate the influence of aging on steroid hormone production in skeletal muscles in response to resistance training. Male F344 rats, aged 4 months (young) and 22 months (old), were randomized into the sedentary and t...
Changes in adrenoceptor expression level contribute to the cellular plasticity of glioblastoma cells [0.03%]
肾上腺受体表达水平的改变有助于胶质母细胞瘤细胞的可塑性
Yutaro Asaka,Toshio Masumoto,Atsuhito Uneda et al.
Yutaro Asaka et al.
Glioblastoma cells are known to regulate their cellular plasticity in response to their surrounding microenvironment, but it is not fully understood what factors contribute to the cells' changing plasticity. Here, we found that glioblastoma...
Yasunori Takayama
Yasunori Takayama
Some thermosensitive transient receptor potential (TRP) channels form a protein complex with anoctamin 1 (ANO1, also called TMEM16A). TRP channels have high calcium permeability, and the calcium entering cells through TRP channel activation...
C-fiber-related brain responses evoked by laser heat pulses applied to the back [0.03%]
激光热脉冲作用于背部时与C纤维有关的脑部反应
Benjamin Provencher,Mathieu Piché
Benjamin Provencher
The aim of the present study was to examine C-fiber-related brain responses evoked by laser heat stimuli applied to the lumbar area, and to determine the stimulation protocol that produces the most reliable responses. Thirty healthy volunte...