Distinct molecular profiles in human aortic smooth muscle cells under cyclic stretch and hydrostatic pressure [0.03%]
人主动脉平滑肌细胞在周期拉伸和静水压下的不同分子特征
Takahiro Kusume,Hana Inoue,Noriaki Arakawa et al.
Takahiro Kusume et al.
Vascular smooth muscle cells are constantly subjected to cyclic stretch and hydrostatic pressure in vivo, yet the molecular responses to these stimuli remain incompletely understood. We performed transcriptome and secretome analyses to char...
Inter- and intra-site reliability of forearm sweating induced by pilocarpine iontophoresis [0.03%]
毛果芸香碱电穿孔诱发前臂出汗的同测和跨测可靠性
Hui Wang,Lu Meng,Junto Otsuka et al.
Hui Wang et al.
We examined the inter- and intra-site reliability of pilocarpine-induced forearm sweat rate at three concentrations. Under thermoneutral conditions, 10 males and 4 females received 0.001%, 0.01%, and 1% pilocarpine via iontophoresis at the ...
Rapid water transfer from extracellular to intracellular spaces following oral ingestion [0.03%]
口服给药后水从细胞外空间快速转移到细胞内空间
Hiroyuki Terawaki,Masahiko Y Kida
Hiroyuki Terawaki
Research on the effects of oral ingestion on extracellular and intracellular water balance is scarce. To measure the postprandial change in extracellular-intracellular water balance, 28 healthy adults (mean age 39 years, 20 women, 8 men) we...
Effects of empagliflozin alone and in combination with exercise on the soleus muscle in obese type 2 diabetic rats [0.03%]
恩格列净或与运动联用对肥胖2型糖尿病大鼠腓肠肌的影响
Kazuho Inoue,Saori Sekiguchi,Yuji Ogura et al.
Kazuho Inoue et al.
This study assessed whether empagliflozin (EMPA) combined with endurance exercise further improves the soleus muscle in spontaneously diabetic Torii fatty rats, a model of obese type 2 diabetes. Male rats were divided into untreated control...
Effects of serotonin transporters on myocardial cell injury during ischemia/reperfusion in rats [0.03%]
大鼠心肌缺血再灌注损伤中5-HT转运蛋白的影响作用研究
Yoshimasa Kishi,Shuji Shimizu,Yosuke Kuroko et al.
Yoshimasa Kishi et al.
Serotonin (5-HT) reuptake in the heart is mediated by the platelet serotonin reuptake transporter (SERT) and the cardiomyocyte plasma membrane monoamine transporter (PMAT). However, the specific roles of these transporters in myocardial cel...
Slow and fast locomotor muscle adaptations to sustained intermittent hypoxaemia [0.03%]
间歇性低氧暴露诱导慢肌和快肌纤维的适应性变化
Lise Paprzycki,Vincianne Jenart,Alexandre Legrand et al.
Lise Paprzycki et al.
Episodic hypoxaemia is associated with muscle dysfunction in respiratory insufficiencies, but its effects depend on the hypoxia/reoxygenation pattern. Sustained Intermittent Hypoxemia (SIH) characterizes a large subgroup of COPD patients, y...
Contrasting response of polyamine metabolic enzymes underlying fiber-type specific volume regulation in the skeletal muscle with endurance exercise [0.03%]
耐力运动下骨骼肌不同类型纤维体积调节中聚胺代谢酶的差异反应机制研究
Maki Yamaguchi,Makiko Ohkido,Naoya Nakahara et al.
Maki Yamaguchi et al.
To explore the role of polyamine metabolism in muscle-type-specific hypertrophy, we analyzed changes in the expression profiles of polyamine metabolic enzymes and key enzymes for muscle metabolism induced by voluntary wheel running exercise...
Pharmaceutical agents targeting KATP channel modulate sweet taste sensitivity in mice [0.03%]
靶向KATP通道的药物可调节小鼠对甜味的感觉灵敏度
Chika Sawai,Kuanyu Wang,Kengo Horie et al.
Chika Sawai et al.
Sweet detection involves at least two mechanisms: a G-protein coupled sweet taste receptor (Tas1r2/Tas1r3) and glucose transporters. As in pancreatic β-cells, glucose transport may lead to closure of ATP-sensitive potassium (KATP) channels...
Changes in palmitate- and stearate-containing glycerophospholipids in skeletal muscle during clenbuterol-induced fast-twitch fiber transition and hypertrophy [0.03%]
克仑特罗诱导的快速收缩肌纤维类型转变和增大的肌糖原磷脂脂肪酸组成变化
Yuna Suzuki,Tomoki Sato,Satoshi Ohuchi et al.
Yuna Suzuki et al.
Fast- and slow-twitch skeletal muscle fibers exhibit distinct glycerophospholipid compositions, and slow-twitch transition is accompanied by characteristic changes in glycerophospholipid molecular species. However, whether glycerophospholip...
Cuong Nguyen Van,Duc Le Trung,Takeru Okamoto et al.
Cuong Nguyen Van et al.
Attention is crucial for motor performance because it enhances task-relevant processing while suppressing distractions. However, physiological markers of attentional engagement during motor activity remain incompletely understood. The prese...