Immunogenetic diversity of two South Asian cohorts, from Pakistan and India [0.03%]
来自巴基斯坦和印度两个南亚队列的免疫遗传多样性
Katherine M Kichula,Neus Font-Porterias,Nicholas R Pollock et al.
Katherine M Kichula et al.
Having critical roles in immune defense and reproduction, killer cell immunoglobulin-like receptors (KIR) and their human leukocyte antigen (HLA) class I ligands are encoded by the most polymorphic regions in the human genome. South Asia co...
Integrating immunogenetic stratification and follicular immune dynamics: an evolving framework for CAR-Treg therapy in antibody-mediated rejection [0.03%]
免疫遗传分层与滤泡免疫动力学的整合：抗体介导排斥反应中CAR-Treg治疗的新兴框架
Nurten Sayin Ekinci,Habibe Sema Arslan Unal
Nurten Sayin Ekinci
One of the leading causes of long-term graft loss following kidney transplantation is antibody-mediated rejection (AMR). In this process, donor-specific antibodies (DSAs), arising either from pre-transplant sensitization or developing de no...
IL10 promoter variants in neurocysticercosis: family-based susceptibility and exploratory genotype-phenotype analyses in Mexican case-parent trios [0.03%]
墨西哥病例父母三联体在神经囊尾蚴病中的易感性及其探索性的基因型表型分析：由IL10启动子变异引起
M Villegas,A Fleury,C Alaez et al.
M Villegas et al.
Given the central role of neuroinflammation in neurocysticercosis (NCC), IL10 promoter variation may influence susceptibility and disease expression. We analyzed rs1800896 (-1082 A > G), rs1800871 (-819C > T), and rs1800872 (-592C > A), tog...
Investigation of ACE gene polymorphism and serum ACE activity in relation to alopecia areata among Iraqi patients [0.03%]
伊拉克脱发患者的ACE基因多态性和血清ACE活性的相关研究
Dalya Jamal Dhahir,Mohammed A Mohammed,Mohammad M F Al-Halbosiy
Dalya Jamal Dhahir
Background: Alopecia areata (AA) is a multifactorial disorder with immune dysregulation and genetic susceptibility, affecting 0.5-2% globally. Objective: ...
Establishing "Glycoantigens" as a cross-field concept in Glycobiology, transfusion, transplant, and immunology [0.03%]
在糖生物学、输血、移植和免疫学中建立“糖抗原”作为跨领域概念
William J Lane
William J Lane
Cell-surface glycans (carbohydrate structures) serve as critical antigens in transfusion and transplantation, yet their study remains fragmented across disciplines. The ABO blood group system, the most clinically tested glycan compatibility...
Association between subclinical atherosclerosis and NLRP3 rs10157379 and rs10754558 genetic variants, inflammatory, and metabolic biomarkers in HIV-1 infection [0.03%]
HIV-1感染中亚临床动脉粥样硬化与NLRP3基因多态性、炎症及代谢标志物的关系
Philipe Quagliato Bellinati,Marcell Alysson Batisti Lozovoy,Tainah Mendes Ahrens et al.
Philipe Quagliato Bellinati et al.
The NLRP3 inflammasome, along with inflammatory and metabolic biomarkers, has been implicated in atherosclerosis. This study aimed to investigate the association between subclinical atherosclerosis and NLRP3 rs10157379 T > C and rs10754558 ...
Blocking the aryl hydrocarbon receptor (AhR) protects CD4+ T cells from Th17/Treg differentiation imbalance through SENP1-mediated deSUMOylation [0.03%]
通过SENP1介导的脱SUMO化保护CD4+T细胞免于Th17/Treg分化失衡及aryl hydrocarbon受体(AhR)阻滞的作用
Jiao Ge,Yan Liu
Jiao Ge
Background: Immune thrombocytopenic purpura (ITP) is the most common autoimmune bleeding disorder in children and poses a serious threat to pediatric health and survival. An imbalance in Th17 and Treg cell differentiation...
Dithiothreitol treatment rescues C1q assay performance by reducing high background [0.03%]
二硫苏糖醇处理通过降低高背景以恢复C1q检测性能
Xiaohai Zhang
Xiaohai Zhang
The presence of donor-specific antibodies (DSAs) to human leukocyte antigen (HLA) is associated with antibody-mediated rejection and reduced graft survival. Donor-specific HLA antibodies can bind to cells of the allograft and cause graft in...
Heightened Frequency of Innate Immunity Risk Alleles in South Indian Diabetics with Urinary Tract Infections [0.03%]
南印度糖尿病伴发泌尿系感染患者中固有免疫风险等位基因频率升高
Priyanka Balaji,M Emmanuel Bhaskar,R Gnanasambandan et al.
Priyanka Balaji et al.
Urinary Tract Infections are an emerging public health concern among individuals with diabetes mellitus, particularly in South Asia where high disease burden, genetic diversity and increasing drug resistance contribute to the progressive in...
Biochemical and cytokine profiles in COVID-19 patients from northeastern Brazil: IL-18BPa as a predictive marker and IL-37 associated with disease severity [0.03%]
巴西东北部新冠肺炎患者的生物化学和细胞因子特征：IL-18BP作为预测性标志物和IL-37与疾病严重程度相关
Heloísa Isabela Leão,Eduardo Davi Lima da Silva,Ryan Cordeiro da Silva et al.
Heloísa Isabela Leão et al.
COVID-19 severity is largely determined by dysregulated host inflammatory responses, yet biomarkers that reflect this immunological imbalance and support clinical risk stratification remain insufficiently defined. The IL-1 cytokine family h...