Blocking the aryl hydrocarbon receptor (AhR) protects CD4+ T cells from Th17/Treg differentiation imbalance through SENP1-mediated deSUMOylation
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Background: Immune thrombocytopenic purpura (ITP) is the most common autoimmune bleeding disorder in children and poses a serious threat to pediatric health and survival. An imbalance in Th17 and Treg cell differentiation leads t... ...