Molybdenum nanodots reprogram inflammatory-driven osteolysis via bone immune remodeling [0.03%]
钼纳米点通过骨免疫重塑重新编程炎症驱动的骨吸收
Zi Fu,Wanting Hao,Xichun Qin et al.
Zi Fu et al.
The translational potential of nanomedicines largely depends on compositional simplicity and scalable synthesis, with structurally intricate systems (e.g., hybrid composites) often struggling in manufacturing standardization. Single-element...
Well-defined electronic configuration cyano-bridged bimetallic nanozyme for cancer catalytic-immunotherapy [0.03%]
具有明确电子构型的氰基桥联双金属纳米酶用于癌症催化免疫治疗研究
Qianqian Wu,Xiaohui Chen,Sitong Wang et al.
Qianqian Wu et al.
Heterobimetallic nanozymes hold great promising in cancer catalytic therapy by leveraging dual-active sites that are electronically coupled. However, their therapeutic potential is limited by high inherent complexity and lack of clarity reg...
A versatile device for in vitro magnetomechanical scaffold stimulation and enhancement of osteochondral differentiation of hMSCs [0.03%]
一种用于体外磁力学支架刺激和增强人源间充质干细胞成软骨分化的多功能设备
Maria Kalogeropoulou,Sophia Dalfino,Milad Takhsha et al.
Maria Kalogeropoulou et al.
Physical stimuli have received significant attention, owing to their capacity to create more biomimetic niches. While dynamic mechanical loading has shown promise in promoting osteogenic and chondrogenic differentiation, magnetic fields hav...
Nano-in-microalgae integrated modular hydrogel system for spatiotemporally targeted oral gene therapy of ulcerative colitis [0.03%]
一种用于溃疡性结肠炎时空靶向口服基因治疗的纳米藻类一体化模块化水凝胶系统
Weili Zhao,Yixin Sun,Jiaqi Yang et al.
Weili Zhao et al.
Small interfering RNAs (siRNAs) have brought revolutionary advances as promising therapeutic candidates for ulcerative colitis, owing to the durable anti-inflammatory efficacy and favorable biocompatibility. Nevertheless, the clinical trans...
Corrigendum to "MiR-138 reprograms dental pulp stem cells into GABAergic neurons via the GATAD2B/MTA3/WNTs axis for stroke treatment" [Biomaterials 325 (2026) 123618] [0.03%]
关于“MiR-138通过GATAD2B/MTA3/WNT轴将牙髓干细胞重编程为GABAergic神经元以治疗卒中”一文的勘误[Biomaterials 325 (2026) 123618]
Heng Zhou,Ping Wen,Ye Liu et al.
Heng Zhou et al.
Published Erratum
Biomaterials. 2025 Nov 24:123858. DOI:10.1016/j.biomaterials.2025.123858 2025
Target anesthesia and surgery induced senescent cell via composite microsphere hydrogels as nose-to-brain amplifiers of platelet factor 4 delivery for neurocognitive dysfunction repair [0.03%]
靶向麻醉和手术诱导的衰老细胞，通过复合微球水凝胶作为鼻脑递送PF4的放大器修复神经认知障碍
Zheng Xie,Zehao Chen,Weifeng Wu et al.
Zheng Xie et al.
Perioperative neurocognitive disorder (PND) is a common complication in older surgical patients, leading to increased neurodegenerative and death risk, augment socioeconomic burdens. Despite its prevalence, the reasons of why this complicat...
Masking macrophage injury sensing via poly I sustained release system reduces inflammation and fibrosis [0.03%]
持续释放poly I的系统屏蔽巨噬细胞损伤感知可降低炎症和纤维化水平
Keyi Chen,Xingjian You,Wei Yu et al.
Keyi Chen et al.
Tissue fibrosis following injury often leads to severe complications in humans. Recent research highlights that macrophage hypermigration and activation play a critical role in fibrosis development. Emerging evidence suggests that macrophag...
Macrophage-to-myofibroblast transition (MMT) - An adverse response to polypropylene mesh implanted for pelvic organ prolapse repair surgery in a non-human primate model [0.03%]
巨噬细胞向肌成纤维细胞转化（MMT）-非人灵长类动物模型中盆底器官脱垂修补术后聚丙烯网片植入的不良反应
Marrisa A Therriault,Katrina Knight,Srividya Kottapalli et al.
Marrisa A Therriault et al.
Surgical repair of pelvic organ prolapse (POP) is often augmented by polypropylene mesh to provide mechanical support to the vagina and improve anatomical outcomes as compared to native tissue repair. However, POP repair surgeries utilizing...
A cannula connecting strategy fostering vascular anastomosis based on mechanical support and biochemical modulation [0.03%]
一种基于机械支撑和生化调控的导管连接策略促进血管吻合
Shengji Gu,Jian Zhou,Qiang Liu et al.
Shengji Gu et al.
Anastomosis is essential in cardiovascular surgery. However, traditional hand-sewn techniques are technically demanding, and existing sutureless methods often result in complications such as thrombosis and delayed healing due to poor mechan...
Short-chain dense brush PEGylation on rigid nanocarriers overcomes anti-PEG antibody recognition for immune-stealth drug delivery [0.03%]
短链密集型刚性聚乙二醇化纳米载体克服抗聚乙二醇抗体作用实现隐形药物传输
Ting-Yu Chen,Chi-Yuan Chang,Li Xu et al.
Ting-Yu Chen et al.
The clinical utility of PEGylated nanomedicines is constrained by anti-polyethylene glycol (PEG) immunity, which drives accelerated blood clearance and infusion reactions. We address this by rationally tuning polymer architecture: a short-c...