Intranasal delivery of engineered macrophage-membrane-coated nanoparticles with enhanced Dectin-1 expression for targeted therapy of cryptococcal meningitis
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Cryptococcal meningitis is a devastating fungal infection of the central nervous system that disproportionately affects immunocompromised individuals and carries high mortality. Amphotericin B (AmB), the clinical gold standard, exhibits potent fungicidal activ... ...
