Isolation, structure elucidation, and absolute configuration of 5,6-dioxygenated aaptamine derivatives from the marine sponge Aaptos sp [0.03%]
来自海洋海绵Aaptos sp中的5,6-二氧代aaptamine衍生物的分离、结构解析及绝对构型确定
Mochamad Muslich Arief,Nalae Kang,A-Young Shin et al.
Mochamad Muslich Arief et al.
A chemical investigation of the Vietnamese marine sponge Aaptos sp. identified eight previously undescribed aaptamines (1-8) and two known analogs (9-10). In particular, derivatives (1-6) feature unusual oxygen-generated stereocenters at C-...
SMART-assisted discovery of scalaranes from the marine sponge Lendenfeldia sp. and its anti-osteoclastogenesis activity [0.03%]
基于SMART技术发现的一种管底海绵Lendenfeldia sp.中的скаlarane及其抗破骨细胞发生作用活性
Quoc Vu Pham,Yu-Chia Chang,You-Song Cheng et al.
Quoc Vu Pham et al.
Marine sponges of the genus Lendenfeldia are known as a rich source of scalarane-type sesterterpenoids with diverse biological activities. In the present study, SMART-guided isolation of scalarane-type sesterterpenoids from the marine spong...
Corrigendum to 'Xuetonlignans E-K, unusual spirobenzofuranoid dibenzocyclooctadiene lignans with hepatoprotective activity from the roots of Kadsura heteroclita' [Phytochemistry 239 (2025) 114594] [0.03%]
《Xuetonlignans E-K的勘误:来自异花木通根中的具有保肝活性的不寻常螺旋苯并菲烷二苯并环辛二烯型木质素》
Wei Su,Xudong Zhou,Hanwen Yuan et al.
Wei Su et al.
Published Erratum
Phytochemistry. 2025 Dec 19:114753. DOI:10.1016/j.phytochem.2025.114753 2025
Sclerohumins G-L: Selective cytotoxic diterpenoids featuring a 4/9-fused ring system from the soft coral Sclerophytum humesi [0.03%]
来自软珊瑚Sclerophytum humesi中的选择性细胞毒二萜类化合物 sclerohumins G–L具有一个稠合的四元/九元环系统
Phuong Vu Luu,Thuy-Tien Thi Phan,Ngoc-Thac Pham et al.
Phuong Vu Luu et al.
Eight previously undescribed terpenoids, including six xeniaphyllane-derived diterpenoids, sclerohumins G-L (1-6), and two norcaryophyllene-type sesquiterpene isomers, norsclerohumins M and N (7 and 8), were isolated from the soft coral Scl...
Cissatriterpenoids D-L, nine undescribed polyhydroxylated oleanane triterpenoids from Cissampelos pareira var. hirsuta [0.03%]
番木瓜亚种中九个新茋三萜类成分
Shuang-Qin Cao,Ru-Yi Pan,Tong-Tong Zhang et al.
Shuang-Qin Cao et al.
Nine undescribed polyhydroxylated oleanane triterpenoids (cissatriterpenoids D-L, 1-9) were isolated from the roots of Cissampelos pareira var. hirsuta. Their structures and absolute configurations were elucidated by extensive spectroscopic...
Sinusiaesenoids A-J, previously undescribed diterpenoids with pro-angiogenic activity from the soft coral Sinularia siaesensis [0.03%]
来自软珊瑚辛纳里亚西氏种的10个新的具促血管生成活性的二萜类成分.sinusiaesenoids A-J
Haiyan Chen,Yongjing Xu,Congcong Zhao et al.
Haiyan Chen et al.
A rearranged diterpenoid with a previously undescribed 16/17(15 → 13)-diabeo carbon skeleton, sinusiaesenoid A (1), and a nitrogenous norxeniaphyllane-type diterpenoid possessing an unprecedented formylpyrrole moiety side chain, sinusiaese...
Discovery of undescribed PCSK9 inhibitory activities in Annonaceous acetogenins from Polyalthia evecta [0.03%]
拟裸实叶树中不可描述的PCSK9抑制剂活性的 annonaceous acetogenin 的新发现
Chae-Yeong An,Chan-Woong Park,Pisey Pel et al.
Chae-Yeong An et al.
Bioassay-guided isolation using a HepG2 cell-based proprotein convertase subtilisin/kexin type 9 (PCSK9) ELISA led to the isolation of four previously unreported (1-4) and six known (5-10) mono-tetrahydrofuran Annonaceous acetogenins from t...
1-Hydroxy dammarane triterpenoids from the aerial parts of Gomphogyne bonii enhance glucose uptake in 3T3-L1 adipocytes through activation of AMP-activated protein kinase [0.03%]
鬼莲草总皂苷茋甲素通过激活腺苷酸活化蛋白激酶促进3T3-L1脂肪细胞葡萄糖摄取作用中的一氢氧杂三萜类成分研究
Phuong-Thien Thuong,Thi-Kim-Quy Ha,Duy-Thuan Nguyen et al.
Phuong-Thien Thuong et al.
A comprehensive phytochemical investigation of the Vietnamese medicinal plant Gomphogyne bonii led to the isolation of ten saponins, including eight previously undescribed dammarane-type saponins (1-8) and the two known oleane-type saponins...
Oxalicpyridones A-D, 2-pyridone alkaloids from a marine-derived fungus Penicillium oxalicum suppressing proliferation and metastasis against small cell lung cancer [0.03%]
来源于海洋真菌Penicillium oxalicum的新吡啶酮类生物碱及其抗小细胞肺癌增殖和转移的作用研究
Xiangliu Chen,Ini Wong,Mengjing Cong et al.
Xiangliu Chen et al.
To explore bioactive specialized metabolites from marine-derived fungi, four previously undescribed 2-pyridone alkaloids, oxalicpyridones A-D (1-4), two unreported tetramic acids, tolypocladenols G and H (5 and 6), together with five known ...
Ailancoumaquinone A and ailancoumarins M-T, undescribed terpenylated coumarins from Ailanthus altissima and their anti-inflammatory activity [0.03%]
取自毒甜槐中的新倍半萜香豆素类化合物及其抗炎活性研究
Da-Le Guo,Li Huang,Hui-Min Zhang et al.
Da-Le Guo et al.
Nine previously undescribed coumarin congeners, including ailancoumaquinone A (1) and ailancoumarins M-T (2-9), were isolated from the root bark of Ailanthus altissima (Mill.) Swingle. Their structures were confirmed through spectral analys...