Chemical constituents of Dendrobium nobile Lindl. and their inhibitory activity on the collagen production in NIH 3T3 cells [0.03%]
石斛兰化学成分及体内抑制胶原蛋白增生活性研究
Jing Xie,Chunying Zhang,Yu Cao et al.
Jing Xie et al.
Dendrobium nobile Lindl. is a major source of "Shi-Hu" listed in the 'Chinese Pharmacopoeia'. D. nobile has been cultivated in large areas. A comprehensive investigation of the chemical constituents of D. nobile is pivotal for production, e...
Guaiane sesquiterpenes from Lindera glauca: isolation, structural elucidation, and hepatoprotective effect [0.03%]
光叶细柱香桂薁类倍半萜的分离、结构鉴定及保肝活性研究
Lan-Lan Nie,Xin-Yu Sun,Qing Shi et al.
Lan-Lan Nie et al.
Nine undescribed guaiane sesquiterpenoids named linderaguaianoids A-I, together with thirteen reported analogues, were isolated from the roots of Lindera glauca. Their structures were fully elucidated by spectroscopic techniques, single-cry...
Isolation, structural elucidation, and biological evaluation of anti-inflammatory and cytotoxic compounds from Ligusticum wallichii [0.03%]
防炎和抗肿瘤化合物白芷中的分离、结构解析及生物评价
Ninh Khac Thanh Tung,Nguyen Thi Tu Oanh,Tran Huu Giap et al.
Ninh Khac Thanh Tung et al.
Ligusticum wallichii Franch., an oriental medicinal herb widely used throughout East Asian countries, is well recognized for its therapeutic potential in treating cardiovascular, inflammatory, and neurodegenerative diseases. In this study, ...
Diterpenoids from the flower buds of Daphne genkwa induced the pyroptosis of HCT-116 cells by inhibiting STAT3 phosphorylation [0.03%]
从黄花杜鹃花芽中分离的二萜类化合物通过抑制STAT3磷酸化诱导HCT-116细胞发生焦亡
Zuijie Cheng,Juan Wu,Xiaolan Chen et al.
Zuijie Cheng et al.
Tigliane and daphnane diterpenoids are structurally and biologically diverse natural products mainly found in the Thymelaeaceae and Euphorbiaceae plant families, characterized by polyoxygenated functionalities in the polycyclic skeleton. In...
C-20 Oxidized furylethyl clerodane diterpenes isolated from Croton argyratus and their antifungal activity [0.03%]
来源于卷曲叶毛脉笔木的富马酸基倍半萜类成分及其抗真菌活性研究
Kanami Watanabe,Rintaro Muroda,Daisuke Yamanaka et al.
Kanami Watanabe et al.
A thorough phytochemical study of a 50% MeOH/CH2Cl2 extract of Croton argyratus (Euphorbiaceae) yielded 17 furylethyl clerodanes, crotargyric acids A-L (1-12), ent-heteroscyphsic acids B, C, and F (13-15), crotargyrol (16), and biscrotargyr...
Diverse bioactive metabolites from Callicarpa longifolia var. floccosa: terpenoids, polyketide, and callilongiflocin A as a potent anti-inflammatory diterpenoid targeting IL-17/TNF-α/MAPK signaling with anti-psoriatic activity [0.03%]
大叶灰毛菍的生物活性次生代谢产物研究：三类倍半萜、聚酮及一类抗炎新天然茋类化合物
Ting Liu,Xiao-Lu Wu,Lian-Chun Li et al.
Ting Liu et al.
Seven previously undescribed compounds comprising four diterpenoids (1-4), two sesquiterpenoids (5, 6), and one polyketide (7), together with four known diterpenoids (8-11), were isolated from Callicarpa longifolia Lamk. var. floccosa Schau...
Metabolomics-guided discovery of previously undescribed lupane-type triterpenoids with anti-inflammatory activity from Mallotus repandus (Willd.) Müll. Arg [0.03%]
代谢组学指导的毛核木素马洛托林抗炎活性 Lupane型三萜类成分发现及作用机制研究
Wenyi Li,Shiyun Liu,Hanyan Cai et al.
Wenyi Li et al.
Guided by molecular networking based on liquid chromatography with tandem mass spectrometry (LC-MS/MS), nine previously undescribed lupane-type triterpenoids (1-9), together with six known analogs (10-15), were isolated from the 95% ethanol...
Structurally diverse flavonoids from the seeds of Astragalus complanatus with ferroptosis regulation via the NOX4/Nrf2 axis in neural cells [0.03%]
牻牛儿芽 astragalus complanatus 种子中的结构多样的黄酮类化合物通过NOX4/Nrf2轴调节神经细胞铁死亡抗氧化作用机制研究
Kang-Hong Zhao,Xu-Tong Fang,Yue-Tong Zhu et al.
Kang-Hong Zhao et al.
The seeds of Astragalus complanatus R. Br. (SAC), a medicinal food homologous resource, are widely distributed and utilized in China. A phytochemical investigation of the seeds of SAC afforded 47 flavonoids, including eight previously undes...
Previously unreported monomeric sorbicillinoids from Trichoderma reesei SCNU-F0042 as α-glucosidase inhibitors and antioxidants: isolation, bioactivity, and potential mechanisms [0.03%]
一种新的单体己烯大霉素类似物：分离、活性及潜在机制研究
Zhengming Liu,Chen Chen,Hao Jia et al.
Zhengming Liu et al.
Diabetes mellitus has caused serious health problems worldwide due to its high prevalence and associated complications. Natural products are considered as an unsurpassed source for lead compounds. This work aims at exploring potential struc...
Sesquiterpenoids isolated from the leaves of Aucklandia costus and their inhibitory effect on nitric oxide production [0.03%]
宽叶丝石竹叶片中倍半萜类化合物的分离及其对一氧化氮产生的抑制作用
Long-Gao Xiao,Tao-Bin He,Yan-Xi Li et al.
Long-Gao Xiao et al.
Twelve previously undescribed sesquiterpenoids (named auckcostusnoids A-L, 1-12), together with eighteen known analogues (13-30), were isolated from the leaves of Aucklandia costus. The structures of compounds 1-12 were elucidated through c...