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Isolation, structure elucidation, and absolute configuration of 5,6-dioxygenated aaptamine derivatives from the marine sponge Aaptos sp

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A chemical investigation of the Vietnamese marine sponge Aaptos sp. identified eight previously undescribed aaptamines (1-8) and two known analogs (9-10). In particular, derivatives (1-6) feature unusual oxygen-generated stereocenters at C-5 and C-6, rendering... ...