Discovery of undescribed PCSK9 inhibitory activities in Annonaceous acetogenins from Polyalthia evecta
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Bioassay-guided isolation using a HepG2 cell-based proprotein convertase subtilisin/kexin type 9 (PCSK9) ELISA led to the isolation of four previously unreported (1-4) and six known (5-10) mono-tetrahydrofuran Annonaceous acetogenins from the branches of Polya... ...
